Ruiyang Ma1, Hong Chen2, Tengfei Zhou1, Xiyan Chen1, Chaoling Wang3, Yijin Chen4, Songlin Rao5, Lin Ge6, Mei Lin7. 1. Undergraduate Student, West China School of Stomatology, Sichuan University. 2. Graduate Student, State Key Laboratory of Oral Diseases, Sichuan University. 3. Graduate Student, Department of Statistics, School of Mathematical Sciences, Sichuan University. 4. Undergraduate Student, School of Computer Sciences, Sichuan University. 5. Undergraduate Student, School of Mathematical Sciences, Sichuan University. 6. Associate Professor, Department of Oral medicine, West China School of Stomatology, Sichuan University. 7. Professor, Department of Oral medicine, West China School of Stomatology, Sichuan University. Electronic address: Linmei2.k@163.com.
Abstract
OBJECTIVE: In this study, we conducted a questionnaire-based survey at Sichuan University to investigate the potential effects of bedtime on recurrent aphthous stomatitis (RAS). STUDY DESIGN: An anonymous self-designed questionnaire was adopted to investigate the association between bedtime and RAS in college students at Sichuan University. Statistical analyses were used to identify risk factors for RAS and to explore the relationship between bedtime and RAS. RESULTS: One thousand six students were investigated. High frequency of colds (odds ratio [OR] 2.17; 95% confidence interval [CI] 1.52-3.10; P < .001) and bedtime after 11 p.m. (OR 16.55; 95% CI 6.49-42.16; P < .001) were independent risk factors for RAS recurrence, but family history, stress, bad relationships with roommates, and gastrointestinal disease were not. Moreover, increased frequency of bedtime after 11 p.m. (τ > 0; P < .05), as well as longer cumulative time from 11 p.m. to bedtime (R > 0; P < .05), was correlated with increased severity of ulcers. CONCLUSION: Bedtime after 11 p.m. not only served as an independent risk factor but both its frequency and cumulative time were also associated with severity of RAS in college students.
OBJECTIVE: In this study, we conducted a questionnaire-based survey at Sichuan University to investigate the potential effects of bedtime on recurrent aphthous stomatitis (RAS). STUDY DESIGN: An anonymous self-designed questionnaire was adopted to investigate the association between bedtime and RAS in college students at Sichuan University. Statistical analyses were used to identify risk factors for RAS and to explore the relationship between bedtime and RAS. RESULTS: One thousand six students were investigated. High frequency of colds (odds ratio [OR] 2.17; 95% confidence interval [CI] 1.52-3.10; P < .001) and bedtime after 11 p.m. (OR 16.55; 95% CI 6.49-42.16; P < .001) were independent risk factors for RAS recurrence, but family history, stress, bad relationships with roommates, and gastrointestinal disease were not. Moreover, increased frequency of bedtime after 11 p.m. (τ > 0; P < .05), as well as longer cumulative time from 11 p.m. to bedtime (R > 0; P < .05), was correlated with increased severity of ulcers. CONCLUSION: Bedtime after 11 p.m. not only served as an independent risk factor but both its frequency and cumulative time were also associated with severity of RAS in college students.
Authors: Kaiyuan Xu; Chongchong Zhou; Fan Huang; Ning Duan; Yanyi Wang; Lichun Zheng; Xiang Wang; Wenmei Wang Journal: J Int Med Res Date: 2021-05 Impact factor: 1.671