OBJECTIVE: To prospectively evaluate the effect of different types of bariatric surgery on lipid profile. METHODS: Total cholesterol (TC), High-Density-Lipoprotein cholesterol (HDLc), Low-Density-Lipoprotein cholesterol (LDLc) and triglycerides (TG) levels were evaluated before surgery and at 3 different post-operative time-points (3, 6 and 12 months) in consecutive obese subjects undergoing mini-gastric bypass (MGB) or sleeve gastrectomy (SG). RESULTS: At baseline, 74 MGB and 86 SG subjects were comparable for lipid profile and prevalence of hypercholesterolemia/hypertriglyceridemia. During the post-operative follow-up, both MGB and SG subjects showed significant changes in lipid profile. However, at 3 months, MGB patients showed higher changes in TC (β = 0.179, p = 0.022) and TG (β = 0.265, p = 0.001) than those undergoing SG. At 6-month post-operative follow-up, these differences were confirmed only for TC. After a 12-month follow-up, MGB and SG were entirely comparable for changes in lipid profile with the exception of HDLc, whose changes were higher in SG group (β = 0.130, p = 0.039). Overall, the probability to normalize lipid profile during the 12-month follow-up was similar in MGB and in SG patients (OR:1.24, 95%CI:0.41-3.76, p = 0.689). CONCLUSION: Despites some differences at 3-6 post-operative months, during a 12-month follow-up, SG and MGB showed a similar efficacy in the improvement of lipid profile of obese patients.
OBJECTIVE: To prospectively evaluate the effect of different types of bariatric surgery on lipid profile. METHODS: Total cholesterol (TC), High-Density-Lipoprotein cholesterol (HDLc), Low-Density-Lipoprotein cholesterol (LDLc) and triglycerides (TG) levels were evaluated before surgery and at 3 different post-operative time-points (3, 6 and 12 months) in consecutive obese subjects undergoing mini-gastric bypass (MGB) or sleeve gastrectomy (SG). RESULTS: At baseline, 74 MGB and 86 SG subjects were comparable for lipid profile and prevalence of hypercholesterolemia/hypertriglyceridemia. During the post-operative follow-up, both MGB and SG subjects showed significant changes in lipid profile. However, at 3 months, MGB patients showed higher changes in TC (β = 0.179, p = 0.022) and TG (β = 0.265, p = 0.001) than those undergoing SG. At 6-month post-operative follow-up, these differences were confirmed only for TC. After a 12-month follow-up, MGB and SG were entirely comparable for changes in lipid profile with the exception of HDLc, whose changes were higher in SG group (β = 0.130, p = 0.039). Overall, the probability to normalize lipid profile during the 12-month follow-up was similar in MGB and in SG patients (OR:1.24, 95%CI:0.41-3.76, p = 0.689). CONCLUSION: Despites some differences at 3-6 post-operative months, during a 12-month follow-up, SG and MGB showed a similar efficacy in the improvement of lipid profile of obesepatients.
Authors: Maurizio De Luca; Giacomo Piatto; Giovanni Merola; Jacques Himpens; Jean-Marc Chevallier; Miguel-A Carbajo; Kamal Mahawar; Alberto Sartori; Nicola Clemente; Miguel Herrera; Kelvin Higa; Wendy A Brown; Scott Shikora Journal: Obes Surg Date: 2021-05-03 Impact factor: 4.129
Authors: Maurizio De Luca; Tiffany Tie; Geraldine Ooi; Kelvin Higa; Jacques Himpens; Miguel-A Carbajo; Kamal Mahawar; Scott Shikora; Wendy A Brown Journal: Obes Surg Date: 2018-05 Impact factor: 4.129
Authors: Mario Musella; Jan Apers; Karl Rheinwalt; Rui Ribeiro; Emilio Manno; Francesco Greco; Michal Čierny; Marco Milone; Carla Di Stefano; Sahin Guler; Isa Mareike Van Lessen; Anabela Guerra; Mauro Natale Maglio; Riccardo Bonfanti; Radoslava Novotna; Guido Coretti; Luigi Piazza Journal: Obes Surg Date: 2016-05 Impact factor: 4.129
Authors: Miguel A Carbajo; Arlett Fong-Hirales; Enrique Luque-de-León; Juan Francisco Molina-Lopez; Javier Ortiz-de-Solórzano Journal: Surg Endosc Date: 2016-06-17 Impact factor: 4.584