Literature DB >> 25576676

Forensic intelligence for medicine anti-counterfeiting.

Klara Dégardin1, Yves Roggo2, Pierre Margot3.   

Abstract

Medicine counterfeiting is a crime that has increased in recent years and now involves the whole world. Health and economic repercussions have led pharmaceutical industries and agencies to develop many measures to protect genuine medicines and differentiate them from counterfeits. Detecting counterfeit is chemically relatively simple for the specialists, but much more information can be gained from the analyses in a forensic intelligence perspective. Analytical data can feed criminal investigation and law enforcement by detecting and understanding the criminal phenomenon. Profiling seizures using chemical and packaging data constitutes a strong way to detect organised production and industrialised forms of criminality, and is the focus of this paper. Thirty-three seizures of a commonly counterfeited type of capsule have been studied. The results of the packaging and chemical analyses were gathered within an organised database. Strong linkage was found between the seizures at the different production steps, indicating the presence of a main counterfeit network dominating the market. The interpretation of the links with circumstantial data provided information about the production and the distribution of counterfeits coming from this network. This forensic intelligence perspective has the potential to be generalised to other types of products. This may be the only reliable approach to help the understanding of the organised crime phenomenon behind counterfeiting and to enable efficient strategic and operational decision making in an attempt to dismantle counterfeit network.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Chemical composition; Counterfeit medicines; Operational decision-making; Packaging; Profiling; Seizure information

Mesh:

Substances:

Year:  2014        PMID: 25576676     DOI: 10.1016/j.forsciint.2014.11.015

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  4 in total

1.  Analysis of trace amounts of adulterants found in powders/supplements utilizing Raman spectroscopy coupled to direct analyte-probed nanoextraction-nanospray ionization-mass spectrometry.

Authors:  Chinyere N Nnaji; Phillip M Mach; Jason S Acheampong; Travis M Falconer; Guido F Verbeck
Journal:  Anal Methods       Date:  2016-05-17       Impact factor: 2.896

2.  Quantitative screening of the pharmaceutical ingredient for the rapid identification of substandard and falsified medicines using reflectance infrared spectroscopy.

Authors:  Graham Lawson; John Ogwu; Sangeeta Tanna
Journal:  PLoS One       Date:  2018-08-10       Impact factor: 3.240

3.  Rapid authentication of pharmaceuticals via DNA tagging and field detection.

Authors:  Lawrence Jung; Michael E Hogan; Yuhua Sun; Benjamin Minghwa Liang; James A Hayward
Journal:  PLoS One       Date:  2019-06-13       Impact factor: 3.240

4.  An exploratory assessment of the legislative framework for combating counterfeit medicines in South Africa.

Authors:  R J Moshoeshoe; G M Enslin; D R Katerere
Journal:  J Pharm Policy Pract       Date:  2022-01-05
  4 in total

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