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Literature DB >> 25575079

Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.

Marli Silva¹, Laurence Daheron², Hannah Hurley³, Kim Bure⁴, Richard Barker³, Andrew J Carr⁵, David Williams⁶, Hae-Won Kim⁷, Anna French¹, Pete J Coffey⁸, Justin J Cooper-White⁹, Brock Reeve², Mahendra Rao¹⁰, Evan Y Snyder¹¹, Kelvin S Ng¹², Benjamin E Mead¹², James A Smith¹³, Jeffrey M Karp¹², David A Brindley¹⁴, Ivan Wall¹⁵.

Abstract

Induced pluripotent stem cells (iPSCs) have the potential to transform drug discovery and healthcare in the 21(st) century. However, successful commercialization will require standardized manufacturing platforms. Here we highlight the need to define standardized practices for iPSC generation and processing and discuss current challenges to the robust manufacture of iPSC products.

Mesh：

Year: 2015 PMID： 25575079 DOI： 10.1016/j.stem.2014.12.013

Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633

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Cited

18 in total

1. Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.

Authors: Ester Perales-Clemente; Alexandra N Cook; Jared M Evans; Samantha Roellinger; Frank Secreto; Valentina Emmanuele; Devin Oglesbee; Vamsi K Mootha; Michio Hirano; Eric A Schon; Andre Terzic; Timothy J Nelson
Journal: EMBO J Date: 2016-07-19 Impact factor: 11.598

Review 2. Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.

Authors: Kai-C Sonntag; Bin Song; Nayeon Lee; Jin Hyuk Jung; Young Cha; Pierre Leblanc; Carolyn Neff; Sek Won Kong; Bob S Carter; Jeffrey Schweitzer; Kwang-Soo Kim
Journal: Prog Neurobiol Date: 2018-04-11 Impact factor: 11.685

3. Essential design considerations for the resazurin reduction assay to noninvasively quantify cell expansion within perfused extracellular matrix scaffolds.

Authors: Joseph S Uzarski; Michael D DiVito; Jason A Wertheim; William M Miller
Journal: Biomaterials Date: 2017-02-16 Impact factor: 12.479

Review 4. Utilising Induced Pluripotent Stem Cells in Neurodegenerative Disease Research: Focus on Glia.

Authors: Katrina Albert; Jonna Niskanen; Sara Kälvälä; Šárka Lehtonen
Journal: Int J Mol Sci Date: 2021-04-21 Impact factor: 5.923

Review 5. Bringing the age-related macular degeneration high-risk allele age-related maculopathy susceptibility 2 into focus with stem cell technology.

Authors: Shuo Sun; ZhiQing Li; Patrick Glencer; BinCui Cai; XiaoMin Zhang; Jin Yang; XiaoRong Li
Journal: Stem Cell Res Ther Date: 2017-06-06 Impact factor: 6.832

6. A basis for comparison: sensitive authentication of stem cell derived RPE using physiological responses of intact RPE monolayers.

Authors: Kiyoharu J Miyagishima; Qin Wan; Sheldon S Miller; Kapil Bharti
Journal: Stem Cell Transl Investig Date: 2017-01-24

Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.

1. Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.

Review 2. Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.

3. Essential design considerations for the resazurin reduction assay to noninvasively quantify cell expansion within perfused extracellular matrix scaffolds.

Review 4. Utilising Induced Pluripotent Stem Cells in Neurodegenerative Disease Research: Focus on Glia.

Review 5. Bringing the age-related macular degeneration high-risk allele age-related maculopathy susceptibility 2 into focus with stem cell technology.

6. A basis for comparison: sensitive authentication of stem cell derived RPE using physiological responses of intact RPE monolayers.

Review 7. Setting Up a Haplobank: Issues and Solutions.

Review 8. Chemicals as the Sole Transformers of Cell Fate.

Review 9. The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside.

Review 10. Induced Pluripotent Stem (iPS) Cells in Dentistry: A Review.