Literature DB >> 25574423

Trace cancer biomarker quantification using polystyrene-functionalized gold nanorods.

Jian Wu1, Wei Li2, Ghazal Hajisalem1, Ariella Lukach3, Eugenia Kumacheva3, Fraser Hof2, Reuven Gordon1.   

Abstract

We demonstrate the application of polystyrene-functionalized gold nanorods (AuNRs) as a platform for surface enhanced Raman scattering (SERS) quantification of the exogenous cancer biomarker Acetyl Amantadine (AcAm). We utilize the hydrophobicity of the polystyrene attached to the AuNR surface to capture the hydrophobic AcAm from solution, followed by drying and detection using SERS. We achieve a detection limit of 16 ng/mL using this platform. This result shows clinical potential for low-cost early cancer detection.

Entities:  

Keywords:  (240.6680) Surface plasmons; (240.6695) Surface-enhanced Raman scattering; (280.4788) Optical sensing and sensors

Year:  2014        PMID： 25574423      PMCID： PMC4285590          DOI： 10.1364/BOE.5.004101

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  21 in total

1.  Quantitative analysis of thymine with surface-enhanced Raman spectroscopy and partial least squares (PLS) regression.

Authors:  Lei Zhang; Qingqing Li; Wei Tao; Bohao Yu; Yiping Du
Journal:  Anal Bioanal Chem       Date:  2010-08-19       Impact factor: 4.142

2.  Precise subnanometer plasmonic junctions for SERS within gold nanoparticle assemblies using cucurbit[n]uril "glue".

Authors:  Richard W Taylor; Tung-Chun Lee; Oren A Scherman; Ruben Esteban; Javier Aizpurua; Fu Min Huang; Jeremy J Baumberg; Sumeet Mahajan
Journal:  ACS Nano       Date:  2011-05-06       Impact factor: 15.881

3.  Probing dynamic generation of hot-spots in self-assembled chains of gold nanorods by surface-enhanced Raman scattering.

Authors:  Anna Lee; Gustavo F S Andrade; Aftab Ahmed; Michele L Souza; Neil Coombs; Ethan Tumarkin; Kun Liu; Reuven Gordon; Alexandre G Brolo; Eugenia Kumacheva
Journal:  J Am Chem Soc       Date:  2011-04-22       Impact factor: 15.419

4.  Controlling the degree of polymerization, bond lengths, and bond angles of plasmonic polymers.

Authors:  Ariella Lukach; Kun Liu; Heloise Therien-Aubin; Eugenia Kumacheva
Journal:  J Am Chem Soc       Date:  2012-11-01       Impact factor: 15.419

5.  Spermidine/spermine n(1)-acetyltransferase catalyzes amantadine acetylation.

Authors:  A P Bras; J Jänne; C W Porter; D S Sitar
Journal:  Drug Metab Dispos       Date:  2001-05       Impact factor: 3.922

6.  Gold nanorods with sub-nanometer separation using cucurbit[n]uril for SERS applications.

Authors:  Samuel T Jones; Richard W Taylor; Rubén Esteban; Enass K Abo-Hamed; Paul H H Bomans; Nico A J M Sommerdijk; Javier Aizpurua; Jeremy J Baumberg; Oren A Scherman
Journal:  Small       Date:  2014-07-28       Impact factor: 13.281

7.  Gold nanorods with finely tunable longitudinal surface plasmon resonance as SERS substrates.

Authors:  S L Smitha; K G Gopchandran; T R Ravindran; V S Prasad
Journal:  Nanotechnology       Date:  2011-05-17       Impact factor: 3.874

8.  Quantification of an exogenous cancer biomarker in urinalysis by Raman spectroscopy.

Authors:  Guangyi Cao; Ghazal Hajisalem; Wei Li; Fraser Hof; Reuven Gordon
Journal:  Analyst       Date:  2014-11-07       Impact factor: 4.616

9.  Inkjet-printed paper-based SERS dipsticks and swabs for trace chemical detection.

Authors:  Wei W Yu; Ian M White
Journal:  Analyst       Date:  2013-02-21       Impact factor: 4.616

Review 10.  Chemical analysis in vivo and in vitro by Raman spectroscopy--from single cells to humans.

Authors:  Sebastian Wachsmann-Hogiu; Tyler Weeks; Thomas Huser
Journal:  Curr Opin Biotechnol       Date:  2009-03-04       Impact factor: 9.740
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