Literature DB >> 25573967

TET2 loss, a rescue of JAK2V617F HSCs.

William Vainchenker1, Isabelle Plo1.   

Abstract

In this issue of Blood, Chen et al and Kameda et al demonstrate that Tet2 loss has 2 effects in Jak2V617F mice: it increases both the severity of the myeloproliferative disorders and the self-renewal properties of the Jak2V617F hematopoietic stem cells (HSCs).

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Year:  2015        PMID: 25573967     DOI: 10.1182/blood-2014-10-606624

Source DB:  PubMed          Journal:  Blood        ISSN: 0006-4971            Impact factor:   22.113


  1 in total

1.  Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia.

Authors:  Liang Huang; Dan Liu; Na Wang; Shaoping Ling; Yuting Tang; Jun Wu; Lingtong Hao; Hui Luo; Xuelian Hu; Lingshuang Sheng; Lijun Zhu; Di Wang; Yi Luo; Zhen Shang; Min Xiao; Xia Mao; Kuangguo Zhou; Lihua Cao; Lili Dong; Xinchang Zheng; Pinpin Sui; Jianlin He; Shanlan Mo; Jin Yan; Qilin Ao; Lugui Qiu; Hongsheng Zhou; Qifa Liu; Hongyu Zhang; Jianyong Li; Jie Jin; Li Fu; Weili Zhao; Jieping Chen; Xin Du; Guoliang Qing; Hudan Liu; Xin Liu; Gang Huang; Ding Ma; Jianfeng Zhou; Qian-Fei Wang
Journal:  Cell Res       Date:  2017-11-17       Impact factor: 25.617

  1 in total

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