Literature DB >> 25573609

Caspases come together over LPS.

Christina Smith1, Xiaohui Wang2, Hang Yin3.   

Abstract

Caspases are cellular executors, initiating cell death. In a recent study, Shi et al. report that caspases 4/5/11 are cytosolic LPS receptors, becoming activated through oligomerization upon interaction with LPS. These findings shed new light on the mechanisms underlying caspase-mediated pyroptosis, and have implications for the development of effective drugs to treat sepsis.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID： 25573609      PMCID： PMC4323722          DOI： 10.1016/j.it.2014.12.007

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  10 in total

1.  The apoptosome activates caspase-9 by dimerization.

Authors:  Cristina Pop; John Timmer; Sabina Sperandio; Guy S Salvesen
Journal:  Mol Cell       Date:  2006-04-21       Impact factor: 17.970

2.  Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

Authors:  Alvin Lu; Venkat Giri Magupalli; Jianbin Ruan; Qian Yin; Maninjay K Atianand; Matthijn R Vos; Gunnar F Schröder; Katherine A Fitzgerald; Hao Wu; Edward H Egelman
Journal:  Cell       Date:  2014-03-13       Impact factor: 41.582

3.  Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.

Authors:  Xin Cai; Jueqi Chen; Hui Xu; Siqi Liu; Qiu-Xing Jiang; Randal Halfmann; Zhijian J Chen
Journal:  Cell       Date:  2014-03-13       Impact factor: 41.582

4.  Inflammatory caspases are innate immune receptors for intracellular LPS.

Authors:  Jianjin Shi; Yue Zhao; Yupeng Wang; Wenqing Gao; Jingjin Ding; Peng Li; Liyan Hu; Feng Shao
Journal:  Nature       Date:  2014-08-06       Impact factor: 49.962

5.  Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

Authors:  Nobuhiko Kayagaki; Michael T Wong; Irma B Stowe; Sree Ranjani Ramani; Lino C Gonzalez; Sachiko Akashi-Takamura; Kensuke Miyake; Juan Zhang; Wyne P Lee; Artur Muszyński; Lennart S Forsberg; Russell W Carlson; Vishva M Dixit
Journal:  Science       Date:  2013-07-25       Impact factor: 47.728

6.  A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis.

Authors:  Todd W Rice; Arthur P Wheeler; Gordon R Bernard; Jean-Louis Vincent; Derek C Angus; Naoki Aikawa; Ignace Demeyer; Stephen Sainati; Nicholas Amlot; Charlie Cao; Masayuki Ii; Hideyasu Matsuda; Kouji Mouri; Jon Cohen
Journal:  Crit Care Med       Date:  2010-08       Impact factor: 7.598

7.  Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling.

Authors:  Zhaoyu Jin; Yun Li; Robert Pitti; David Lawrence; Victoria C Pham; Jennie R Lill; Avi Ashkenazi
Journal:  Cell       Date:  2009-05-07       Impact factor: 41.582

8.  Small-molecule activators of a proenzyme.

Authors:  Dennis W Wolan; Julie A Zorn; Daniel C Gray; James A Wells
Journal:  Science       Date:  2009-11-06       Impact factor: 47.728

9.  Evaluation of lipopolysaccharide aggregation by light scattering spectroscopy.

Authors:  Nuno C Santos; Ana C Silva; Miguel A R B Castanho; J Martins-Silva; Carlota Saldanha
Journal:  Chembiochem       Date:  2003-01-03       Impact factor: 3.164

10.  Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.

Authors:  Jon A Hagar; Daniel A Powell; Youssef Aachoui; Robert K Ernst; Edward A Miao
Journal:  Science       Date:  2013-09-13       Impact factor: 47.728
  10 in total
  8 in total

1.  Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.

Authors:  Christina E Smith; Subada Soti; Torey A Jones; Akihisa Nakagawa; Ding Xue; Hang Yin
Journal:  Cell Chem Biol       Date:  2017-02-23       Impact factor: 8.116

2.  Expression and regulation of alarmin cytokine IL-1α in human retinal pigment epithelial cells.

Authors:  Zong-Mei Bian; Matthew G Field; Susan G Elner; Victor M Elner
Journal:  Exp Eye Res       Date:  2018-03-15       Impact factor: 3.467

3.  Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state.

Authors:  Sarah A Woller; Satheesh B Ravula; Fabio C Tucci; Graham Beaton; Maripat Corr; R Rivkah Isseroff; Athena M Soulika; Marianne Chigbrow; Kelly A Eddinger; Tony L Yaksh
Journal:  Brain Behav Immun       Date:  2016-04-01       Impact factor: 7.217

Review 4.  Nutritional and Nanotechnological Modulators of Microglia.

Authors:  Dusica Maysinger; Issan Zhang
Journal:  Front Immunol       Date:  2016-07-15       Impact factor: 7.561

5.  Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli.

Authors:  Dagmar E Ehrnhoefer; Michael R Hayden; Safia Ladha; Xiaofan Qiu; Lorenzo Casal; Nicholas S Caron
Journal:  Cell Death Discov       Date:  2018-03-12

Review 6.  Antivirals against animal viruses.

Authors:  T G Villa; L Feijoo-Siota; J L R Rama; J M Ageitos
Journal:  Biochem Pharmacol       Date:  2016-09-30       Impact factor: 5.858

7.  Identification of Genes Relevant to Pesticides and Biology from Global Transcriptome Data of Monochamus alternatus Hope (Coleoptera: Cerambycidae) Larvae.

Authors:  Songqing Wu; Xiaoli Zhu; Zhaoxia Liu; Ensi Shao; Carballar-Lejarazú Rebeca; Yajie Guo; Yueting Xiong; Yani Mou; Runxue Xu; Xia Hu; Guanghong Liang; Shuangquan Zou; Xiong Guan; Feiping Zhang
Journal:  PLoS One       Date:  2016-01-27       Impact factor: 3.240

8.  Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs.

Authors:  Alejandra Vargas-Caraveo; Aline Sayd; Javier Robledo-Montaña; Javier R Caso; José L M Madrigal; Borja García-Bueno; Juan C Leza
Journal:  J Neuroinflammation       Date:  2020-01-06       Impact factor: 8.322
  8 in total

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