Literature DB >> 25573428

Predictive model of oral cancer metastasis for different cancer sites and age groups.

Bogahawatte Samarakoon Mudiyanselage Samadarani Siriwardena1, Rasnayaka Mudiynaselage Sumudu Geethika Kumari Rasnayaka1, Yaghma Masood2, Mohd Masood2, Pallegoda Vithanage Ranjith Kumarasiri3, Wanninayake Mudiyanselage Tilakaratne1.   

Abstract

AIM: The high incidence rates for oral cancer (excluding lip) are especially found in the South and South-East Asia. Therefore, the aim of the present study was to investigate the relationship between sex, age, site, and metastasis of a large sample with oral squamous cell carcinoma (OSCC).
METHODS: A total of 989 OSCC treated with neck dissection were selected. All the relevant data were recorded from biopsy request forms. The patients were divided into seven groups, and there were nine different oral sites.
RESULTS: The male-to-female ratio of the sample was 4:1. Most of the patients were aged between 30 and 60 years. Of the 989 patients, approximately 40% patients had metastasis. Age <30 years showed a higher probability of metastasis compared to higher age groups, but it was not statistically significant. Palate cancers had more than 14 times higher chance of metastasis, followed by maxilla (4.6 times) and tongue (2.8 times).
CONCLUSION: The present study provides important information on the metastatic potential of OSCC in different oral sites, and identifies high-risk age groups for metastasis. This will be helpful in planning neck treatment for OSCC.
© 2015 Wiley Publishing Asia Pty Ltd.

Entities:  

Keywords:  age; metastasis; oral cancer; predictive model; site

Mesh:

Year:  2015        PMID: 25573428     DOI: 10.1111/jicd.12145

Source DB:  PubMed          Journal:  J Investig Clin Dent        ISSN: 2041-1618


  3 in total

1.  Ordinal logistic regression model describing factors associated with extent of nodal involvement in oral cancer patients and its prospective validation.

Authors:  Vishwajeet Singh; Sada Nand Dwivedi; S V S Deo
Journal:  BMC Med Res Methodol       Date:  2020-04-26       Impact factor: 4.615

2.  Impact of Histological and Molecular Parameters on Prognosis of Oral Squamous Cell Carcinoma: Analysis of 290 Cases.

Authors:  B S M S Siriwardena; H D N U Karunathilaka; P V R Kumarasiri; W M Tilakaratne
Journal:  Biomed Res Int       Date:  2020-10-14       Impact factor: 3.411

3.  CD147 promotes glucose metabolism, invasion and metastasis via PI3K/AKT pathway in oral squamous cell carcinomas.

Authors:  Yi Huang; Jing Xu; Ying Xu; Li Li; Min Zheng
Journal:  Transl Cancer Res       Date:  2019-08       Impact factor: 1.241

  3 in total

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