Literature DB >> 2557308

Failure of accelerated neutron therapy to control high grade astrocytomas.

K R Saroja1, J Mansell, F R Hendrickson, L Cohen, A Lennox.   

Abstract

Sixty-two patients with high grade malignant astrocytoma were treated with fast neutrons using three different treatment schemes to evaluate the effect of shortening the overall time. Dose and fraction number were kept constant. The total dose was 16-18 neutron Gy delivered in six fractions, weekly for 6 weeks, twice a week over 3-4 weeks, or three times a week over 2 weeks. There were no obvious differences in survival times among the three groups. We conclude that accelerated neutron therapy does not improve survival of patients with grade 3 and 4 astrocytoma.

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Year:  1989        PMID: 2557308     DOI: 10.1016/0360-3016(89)90539-7

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  5 in total

1.  Boron neutron capture enhancement (BNCE) of fast neutron irradiation for glioblastoma: increase of thermal neutron flux with heavy material collimation, a theoretical evaluation.

Authors:  P Paquis; J P Pignol; M Lonjon; N Brassart; A Courdi; P Chauvel; P Grellier; M Chatel
Journal:  J Neurooncol       Date:  1999-01       Impact factor: 4.130

Review 2.  Neuro-oncology index and review (adult primary brain tumors). Radiotherapy, chemotherapy, immunotherapy, photodynamic therapy.

Authors:  M S Mahaley
Journal:  J Neurooncol       Date:  1991-10       Impact factor: 4.130

3.  Immunophenotypic and ultrastructural validation of a new human glioblastoma cell line.

Authors:  André A Schenka; Camila M L Machado; Mariângela C Grippo; Luciano S Queiroz; Natália G M Schenka; Cristiano A Chagas; Liana Verinaud; Pierre Brousset; José Vassallo
Journal:  Cell Mol Neurobiol       Date:  2005-08       Impact factor: 5.046

Review 4.  Boron neutron capture enhanced fast neutron radiotherapy for malignant gliomas and other tumors.

Authors:  T A Buchholz; G E Laramore; K J Stelzer; R Risler; P Wootton; T W Griffin
Journal:  J Neurooncol       Date:  1997-05       Impact factor: 4.130

5.  Boron neutron capture therapy for glioblastoma multiforme using p-boronophenylalanine and epithermal neutrons: trial design and early clinical results.

Authors:  J A Coderre; E H Elowitz; M Chadha; R Bergland; J Capala; D D Joel; H B Liu; D N Slatkin; A D Chanana
Journal:  J Neurooncol       Date:  1997-05       Impact factor: 4.130

  5 in total

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