| Literature DB >> 25572548 |
Roland Kocijan1, Christian Muschitz, Jürgen Rech.
Abstract
Since there is no evidence regarding the efficacy of conventional synthetic disease modifying anti-rheumatic drugs in the improvement of axial spondyloarthritis (SpA), anti-tumor necrosis factors (anti-TNFs) are recommended if nonsteroidal anti-inflammatory drugs fail, or in case of high disease activity. Anti-TNFs show encouraging data regarding pain reduction, improved mobility and quality of life in both ankylosing spondylitis and non-radiographic axial spondyloarthritis. However, withdrawal of anti-TNF therapy leads to relapse of disease activity in SpA. Moreover, osteoproliferation does not seem to be influenced by anti-TNFs.Entities:
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Year: 2015 PMID: 25572548 DOI: 10.1007/s10354-014-0338-1
Source DB: PubMed Journal: Wien Med Wochenschr ISSN: 0043-5341