Literature DB >> 25571916

Time to demand dosimetry for molecular radiotherapy?

D R McGowan1, M J Guy.   

Abstract

Molecular radiotherapy (MRT) has been used clinically for around 75 years. Despite this long history of clinical use, there is no established dosimetry practice for calculating the absorbed dose delivered to tumour targets or to organs at risk. As a result, treatment protocols have often evolved based on experience with relatively small numbers of patients, each receiving a similar administered activity but, potentially, widely varying doses. This is in stark contrast to modern external-beam radiotherapy practice. This commentary describes some of the barriers to MRT dosimetry and gives some opinions on the way forward.

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Year:  2015        PMID： 25571916      PMCID： PMC4651193          DOI： 10.1259/bjr.20140720

Source DB:  PubMed          Journal:  Br J Radiol        ISSN： 0007-1285            Impact factor:   3.039


  10 in total

1.  MIRD pamphlet no. 16: Techniques for quantitative radiopharmaceutical biodistribution data acquisition and analysis for use in human radiation dose estimates.

Authors:  J A Siegel; S R Thomas; J B Stubbs; M G Stabin; M T Hays; K F Koral; J S Robertson; R W Howell; B W Wessels; D R Fisher; D A Weber; A B Brill
Journal:  J Nucl Med       Date:  1999-02       Impact factor: 10.057

Review 2.  Receptor radionuclide therapy with 90Y-[DOTA]0-Tyr3-octreotide (90Y-DOTATOC) in neuroendocrine tumours.

Authors:  Lisa Bodei; Marta Cremonesi; Chiara Grana; Paola Rocca; Mirco Bartolomei; Marco Chinol; Giovanni Paganelli
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-05-19       Impact factor: 9.236

Review 3.  Dosimetry in Peptide radionuclide receptor therapy: a review.

Authors:  Marta Cremonesi; Mahila Ferrari; Lisa Bodei; Giampiero Tosi; Giovanni Paganelli
Journal:  J Nucl Med       Date:  2006-09       Impact factor: 10.057

4.  Five years of molecular radiotherapy growth in the UK: survey results from 2007 to 2012.

Authors:  Bruno Rojas; Claire Hooker; Daniel R McGowan; Matthew J Guy
Journal:  Nucl Med Commun       Date:  2015-08       Impact factor: 1.690

5.  MIRD pamphlet No. 23: quantitative SPECT for patient-specific 3-dimensional dosimetry in internal radionuclide therapy.

Authors:  Yuni K Dewaraja; Eric C Frey; George Sgouros; A Bertrand Brill; Peter Roberson; Pat B Zanzonico; Michael Ljungberg
Journal:  J Nucl Med       Date:  2012-06-28       Impact factor: 10.057

Review 6.  Quantitative SPECT imaging: a review and recommendations by the Focus Committee of the Society of Nuclear Medicine Computer and Instrumentation Council.

Authors:  M S Rosenthal; J Cullom; W Hawkins; S C Moore; B M Tsui; M Yester
Journal:  J Nucl Med       Date:  1995-08       Impact factor: 10.057

Review 7.  Radiation synovectomy revisited.

Authors:  E Deutsch; J W Brodack; K F Deutsch
Journal:  Eur J Nucl Med       Date:  1993-11

8.  Long-term evaluation of renal toxicity after peptide receptor radionuclide therapy with 90Y-DOTATOC and 177Lu-DOTATATE: the role of associated risk factors.

Authors:  Lisa Bodei; Marta Cremonesi; Mahila Ferrari; Monica Pacifici; Chiara M Grana; Mirco Bartolomei; Silvia M Baio; Maddalena Sansovini; Giovanni Paganelli
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-04-22       Impact factor: 9.236

9.  Patient-specific dosimetry for 131I thyroid cancer therapy using 124I PET and 3-dimensional-internal dosimetry (3D-ID) software.

Authors:  George Sgouros; Katherine S Kolbert; Arif Sheikh; Keith S Pentlow; Edward F Mun; Axel Barth; Richard J Robbins; Steven M Larson
Journal:  J Nucl Med       Date:  2004-08       Impact factor: 10.057

10.  Guidelines for the management of thyroid cancer.

Authors:  Petros Perros; Kristien Boelaert; Steve Colley; Carol Evans; Rhordi M Evans; Georgina Gerrard Ba; Jackie Gilbert; Barney Harrison; Sarah J Johnson; Thomas E Giles; Laura Moss; Val Lewington; Kate Newbold; Judith Taylor; Rajesh V Thakker; John Watkinson; Graham R Williams
Journal:  Clin Endocrinol (Oxf)       Date:  2014-07       Impact factor: 3.478
  10 in total
  7 in total

1.  Targeted Molecular Radiotherapy of Pediatric Solid Tumors Using a Radioiodinated Alkyl-Phospholipid Ether Analog.

Authors:  Dana C Baiu; Ian R Marsh; Alexander E Boruch; Ankita Shahi; Saswati Bhattacharya; Justin J Jeffery; Qianqian Zhao; Lance T Hall; Jamey P Weichert; Bryan P Bednarz; Mario Otto
Journal:  J Nucl Med       Date:  2017-07-26       Impact factor: 10.057

2.  SELIMETRY-a multicentre I-131 dosimetry trial: a clinical perspective.

Authors:  Jonathan Wadsley; Rebecca Gregory; Glenn Flux; Kate Newbold; Yong Du; Laura Moss; Andrew Hall; Louise Flanagan; Sarah R Brown
Journal:  Br J Radiol       Date:  2017-03-14       Impact factor: 3.039

3.  Dual-Nuclide Radiopharmaceuticals for Positron Emission Tomography Based Dosimetry in Radiotherapy.

Authors:  Alexander Wurzer; Christof Seidl; Alfred Morgenstern; Frank Bruchertseifer; Markus Schwaiger; Hans-Jürgen Wester; Johannes Notni
Journal:  Chemistry       Date:  2017-09-14       Impact factor: 5.236

4.  Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial.

Authors:  Sarah R Brown; Andrew Hall; Hannah L Buckley; Louise Flanagan; David Gonzalez de Castro; Kate Farnell; Laura Moss; Rebecca Gregory; Kate Newbold; Yong Du; Glenn Flux; Jonathan Wadsley
Journal:  BMC Cancer       Date:  2019-06-14       Impact factor: 4.430

5.  Cherenkov light emission in molecular radiation therapy of the thyroid and its application to dosimetry.

Authors:  Jigar Dubal; Pedro Arce; Christopher South; Lucia Florescu
Journal:  Biomed Opt Express       Date:  2022-03-23       Impact factor: 3.562

6.  The internal dosimetry user group position statement on molecular radiotherapy.

Authors:  Jonathan Gear; Daniel McGowan; Bruno Rojas; Allison J Craig; April-Louise Smith; Catherine J Scott; James Scuffam; Matthew Aldridge; Jill Tipping
Journal:  Br J Radiol       Date:  2021-08-25       Impact factor: 3.629

7.  Chelation with a twist: a bifunctional chelator to enable room temperature radiolabeling and targeted PET imaging with scandium-44.

Authors:  Brett A Vaughn; Shin Hye Ahn; Eduardo Aluicio-Sarduy; Justin Devaraj; Aeli P Olson; Jonathan Engle; Eszter Boros
Journal:  Chem Sci       Date:  2019-11-20       Impact factor: 9.825
  7 in total

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