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Literature DB >> 25571822

Periodontitis: a potential risk factor for Alzheimer's disease.

Abstract

The role of periodontitis as a risk factor for multiple systemic diseases is widely accepted and there is growing evidence of an association between periodontitis and sporadic late onset Alzheimer's disease (SLOAD). Recent epidemiologic, microbiologic and inflammatory findings strengthen this association, indicating that periodontal pathogens are possible contributors to neural inflammation and SLOAD. The aim of this article is to present contemporary evidence of this association.

Entities: Disease

Mesh：

Year: 2015 PMID： 25571822 DOI： 10.1038/sj.bdj.2014.1137

Source DB: PubMed Journal: Br Dent J ISSN： 0007-0610 Impact factor: 1.626

131 in total

1. Dental health, nutritional status and recent-onset dementia in a Korean community population.

Authors: Jae-Min Kim; Robert Stewart; Martin Prince; Sung-Wan Kim; Su-Jin Yang; Il-Seon Shin; Jin-Sang Yoon
Journal: Int J Geriatr Psychiatry Date: 2007-09 Impact factor: 3.485

Review 2. Alzheimer's disease.

Authors: Henry W Querfurth; Frank M LaFerla
Journal: N Engl J Med Date: 2010-01-28 Impact factor: 91.245

3. Tooth loss and periodontal disease predict poor cognitive function in older men.

Authors: Elizabeth Krall Kaye; Aileen Valencia; Nivine Baba; Avron Spiro; Thomas Dietrich; Raul I Garcia
Journal: J Am Geriatr Soc Date: 2010-04 Impact factor: 5.562

4. Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes.

Authors: Judith Miklossy; Andras Kis; Alexandra Radenovic; Lisa Miller; Laszlo Forro; Ralph Martins; Krzysztof Reiss; Nune Darbinian; Pushpa Darekar; Laszlo Mihaly; Kamel Khalili
Journal: Neurobiol Aging Date: 2006-02 Impact factor: 4.673

Review 5. Poor oral health as a chronic, potentially modifiable dementia risk factor: review of the literature.

Authors: James M Noble; Nikolaos Scarmeas; Panos N Papapanou
Journal: Curr Neurol Neurosci Rep Date: 2013-10 Impact factor: 5.081

6. No disease in the brain of a 115-year-old woman.

Authors: Wilfred F A den Dunnen; Wiebo H Brouwer; Eveline Bijlard; Jeanine Kamphuis; Klaas van Linschoten; Ellie Eggens-Meijer; Gert Holstege
Journal: Neurobiol Aging Date: 2008-06-04 Impact factor: 4.673

7. Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.

Authors: Giuseppina Tesco; Young Ho Koh; Eugene L Kang; Andrew N Cameron; Shinjita Das; Miguel Sena-Esteves; Mikko Hiltunen; Shao-Hua Yang; Zhenyu Zhong; Yong Shen; James W Simpkins; Rudolph E Tanzi
Journal: Neuron Date: 2007-06-07 Impact factor: 17.173

Review 8. Interleukin 1 genetics, inflammatory mechanisms, and nutrigenetic opportunities to modulate diseases of aging.

Authors: Kenneth S Kornman
Journal: Am J Clin Nutr Date: 2006-02 Impact factor: 7.045

Review 9. Oral inflammation, tooth loss, risk factors, and association with progression of Alzheimer's disease.

Authors: Sim K Singhrao; Alice Harding; Tal Simmons; Sarita Robinson; Lakshmyya Kesavalu; StJohn Crean
Journal: J Alzheimers Dis Date: 2014 Impact factor: 4.472

10. Drug repositioning: an opportunity to develop novel treatments for Alzheimer's disease.

Authors: Anne Corbett; Gareth Williams; Clive Ballard
Journal: Pharmaceuticals (Basel) Date: 2013-10-11

19 in total

1. Periodontology: a vaccine for periodontopathogens.

Authors: A Dziedzic; R D Wojtyczka
Journal: Br Dent J Date: 2015-03 Impact factor: 1.626

2. Oral and systemic health: Deficits in our knowledge.

Authors: P V Mc Crory
Journal: Br Dent J Date: 2016-02-26 Impact factor: 1.626

3. Impaired innate immune signaling due to combined Toll-like receptor 2 and 4 deficiency affects both periodontitis and atherosclerosis in response to polybacterial infection.

Authors: Sasanka S Chukkapalli; Sriram Ambadapadi; Kyle Varkoly; Jessica Jiron; Jose Ignacio Aguirre; Indraneel Bhattacharyya; Laurence M Morel; Alexandra R Lucas; Lakshmyya Kesavalu
Journal: Pathog Dis Date: 2018-11-01 Impact factor: 3.166

4. Periodontal disease is associated with cognitive dysfunction in aging dogs: A blinded prospective comparison of visual periodontal and cognitive questionnaire scores.

Authors: Curtis Wells Dewey; Mark Rishniw
Journal: Open Vet J Date: 2021-04-19

5. Patients with Chronic Obstructive Pulmonary Disease Suffer from Worse Periodontal Health-Evidence from a Meta-Analysis.

Authors: Quan Shi; Bin Zhang; Helin Xing; Shuo Yang; Juan Xu; Hongchen Liu
Journal: Front Physiol Date: 2018-01-25 Impact factor: 4.566

6. Study protocol: Insight 46 - a neuroscience sub-study of the MRC National Survey of Health and Development.

Authors: Christopher A Lane; Thomas D Parker; Dave M Cash; Kirsty Macpherson; Elizabeth Donnachie; Heidi Murray-Smith; Anna Barnes; Suzie Barker; Daniel G Beasley; Jose Bras; David Brown; Ninon Burgos; Michelle Byford; M Jorge Cardoso; Ana Carvalho; Jessica Collins; Enrico De Vita; John C Dickson; Norah Epie; Miklos Espak; Susie M D Henley; Chandrashekar Hoskote; Michael Hutel; Jana Klimova; Ian B Malone; Pawel Markiewicz; Andrew Melbourne; Marc Modat; Anette Schrag; Sachit Shah; Nikhil Sharma; Carole H Sudre; David L Thomas; Andrew Wong; Hui Zhang; John Hardy; Henrik Zetterberg; Sebastien Ourselin; Sebastian J Crutch; Diana Kuh; Marcus Richards; Nick C Fox; Jonathan M Schott
Journal: BMC Neurol Date: 2017-04-18 Impact factor: 2.474