Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Hepatocellular carcinoma markers in the omics era: the glycomic analysis.

Literature DB >> 25568863

Hepatocellular carcinoma markers in the omics era: the glycomic analysis.

Giulia Malaguarnera¹, Gaetano Bertino¹, Marco Vacante¹, Michele Malaguarnera¹.

Abstract

Recently, Kamiyama et al. performed N-glycan profile in hepatocellular carcinoma (HCC) using the quantitative N-glycomics procedure by way of glycoblotting technology and using an automated glycan purification system. The study showed significant differences of N-glycans profile between healthy volunteers and liver cancer patients. The glycomic approach showed us the usefulness of new tools for identification and application of a new biomarkers for cancer diagnosis and treatment. These findings reveal a new field for future markers discovery.

Entities: Chemical Disease Species

Keywords: Hepatocellular carcinoma (HCC); glycan; glycomic; tumor markers

Year: 2014 PMID： 25568863 PMCID： PMC4273108 DOI： 10.3978/j.issn.2304-3881.2014.07.04

Source DB: PubMed Journal: Hepatobiliary Surg Nutr ISSN： 2304-3881 Impact factor: 7.293

19 in total

1. Glycobiology: Toward Understanding the Function of Sugars.

Authors: Raymond A. Dwek
Journal: Chem Rev Date: 1996-03-28 Impact factor: 60.622

2. Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer.

Authors: Hyun Joo An; Suzanne Miyamoto; Katherine S Lancaster; Crystal Kirmiz; Bensheng Li; Kit S Lam; Gary S Leiserowitz; Carlito B Lebrilla
Journal: J Proteome Res Date: 2006-07 Impact factor: 4.466

3. Separation of isomeric 2-aminopyridine derivatized N-glycans and N-glycopeptides of human serum immunoglobulin G by using a zwitterionic type of hydrophilic-interaction chromatography.

Authors: Yasuhiro Takegawa; Kisaburo Deguchi; Takuro Keira; Hiroki Ito; Hiroaki Nakagawa; Shin-Ichiro Nishimura
Journal: J Chromatogr A Date: 2006-02-28 Impact factor: 4.759

Review 4. Diagnostic and prognostic value of alpha-fetoprotein, des-γ-carboxy prothrombin and squamous cell carcinoma antigen immunoglobulin M complexes in hepatocellular carcinoma.

Authors: G Bertino; S Neri; C M Bruno; A M Ardiri; G S Calvagno; M Malaguarnera; A Toro; M Malaguarnera; S Clementi; N Bertino; I Di Carlo
Journal: Minerva Med Date: 2011-10 Impact factor: 4.806

Review 5. Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours.

Authors: Akira Kobata; Junko Amano
Journal: Immunol Cell Biol Date: 2005-08 Impact factor: 5.126

6. Identification of novel serum biomarkers of hepatocellular carcinoma using glycomic analysis.

Authors: Toshiya Kamiyama; Hideki Yokoo; Jun-Ichi Furukawa; Masaki Kurogochi; Tomoaki Togashi; Nobuaki Miura; Kazuaki Nakanishi; Hirofumi Kamachi; Tatsuhiko Kakisaka; Yosuke Tsuruga; Masato Fujiyoshi; Akinobu Taketomi; Shin-Ichiro Nishimura; Satoru Todo
Journal: Hepatology Date: 2013-04-26 Impact factor: 17.425

Review 7. The role of immunity in elderly cancer.

Authors: Lucia Malaguarnera; Erika Cristaldi; Mariano Malaguarnera
Journal: Crit Rev Oncol Hematol Date: 2009-07-04 Impact factor: 6.312

Review 8. Sweet clearance: involvement of cell surface glycans in the recognition of apoptotic cells.

Authors: Kerstin Sarter; Claudia Mierke; Alexandra Beer; Benjamin Frey; Barbara G Führnrohr; Connie Schulze; Sandra Franz
Journal: Autoimmunity Date: 2007-06 Impact factor: 2.815

9. Carbohydrate 19.9 antigen serum levels in liver disease.

Authors: Gaetano Bertino; Annalisa Maria Ardiri; Giuseppe Stefano Calvagno; Giulia Malaguarnera; Donatella Interlandi; Marco Vacante; Nicoletta Bertino; Francesco Lucca; Roberto Madeddu; Massimo Motta
Journal: Biomed Res Int Date: 2013-10-27 Impact factor: 3.411

10. Glycomic approach for potential biomarkers on prostate cancer: profiling of N-linked glycans in human sera and pRNS cell lines.

Authors: Maria Lorna A de Leoz; Hyun Joo An; Scott Kronewitter; Jaehan Kim; Sean Beecroft; Ruth Vinall; Suzanne Miyamoto; Ralph de Vere White; Kit S Lam; Carlito Lebrilla
Journal: Dis Markers Date: 2008 Impact factor: 3.434

7 in total

Hepatocellular carcinoma markers in the omics era: the glycomic analysis.

1. Glycobiology: Toward Understanding the Function of Sugars.

2. Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer.

3. Separation of isomeric 2-aminopyridine derivatized N-glycans and N-glycopeptides of human serum immunoglobulin G by using a zwitterionic type of hydrophilic-interaction chromatography.

Review 4. Diagnostic and prognostic value of alpha-fetoprotein, des-γ-carboxy prothrombin and squamous cell carcinoma antigen immunoglobulin M complexes in hepatocellular carcinoma.

Review 5. Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours.

6. Identification of novel serum biomarkers of hepatocellular carcinoma using glycomic analysis.

Review 7. The role of immunity in elderly cancer.

Review 8. Sweet clearance: involvement of cell surface glycans in the recognition of apoptotic cells.

9. Carbohydrate 19.9 antigen serum levels in liver disease.

10. Glycomic approach for potential biomarkers on prostate cancer: profiling of N-linked glycans in human sera and pRNS cell lines.

Review 1. Systems Challenges of Hepatic Carcinomas: A Review.

2. Alteration of liver glycopatterns during cirrhosis and tumor progression induced by HBV.

Review 3. Proteomic and metabonomic biomarkers for hepatocellular carcinoma: a comprehensive review.

4. NRAGE is a potential diagnostic biomarker of hepatocellular carcinoma.

5. The Interplay of Inflammatory Processes and Cognition in Alcohol Use Disorders-A Systematic Review.

Review 6. Structural changes of proteins in liver cirrhosis and consequential changes in their function.

Review 7. Use of Mass Spectrometry to Screen Glycan Early Markers in Hepatocellular Carcinoma.