Literature DB >> 25565716

Polioencephalomyelopathy in a mixed breed dog resembling Leigh's disease.

Orit Chai1, Joshua Milgram1, Merav H Shamir1, Ori Brenner1.   

Abstract

A 14-month-old mixed-breed dog was presented with acute onset of exercise intolerance that quickly progressed to quadriparesis. Gross and microscopic autopsy findings indicated a type of degenerative polioencephalomyelopathy resembling subacute necrotizing encephalomyelopathy in dogs or Leigh's disease in humans. This syndrome has previously been reported only in purebred dogs.

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Mesh：

Year:  2015        PMID： 25565716      PMCID： PMC4266058     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  8 in total

1.  Subacute necrotising encephalopathy in an Alaskan husky.

Authors:  J J Wakshlag; A de Lahunta; T Robinson; B J Cooper; O Brenner; T D O'Toole; J Olson; K B Beckman; E Glass; A J Reynolds
Journal:  J Small Anim Pract       Date:  1999-12       Impact factor: 1.522

Review 2.  Hereditary polioencephalomyelopathy of the Australian cattle dog.

Authors:  O Brenner; A de Lahunta; B A Summers; J F Cummings; B J Cooper; B A Valentine; J S Bell
Journal:  Acta Neuropathol       Date:  1997-07       Impact factor: 17.088

3.  A canine encephalomyelopathy with morphological abnormalities in mitochondria.

Authors:  O Brenner; A de Lahunta; J F Cummings; B A Summers; M Monachelli
Journal:  Acta Neuropathol       Date:  1997-10       Impact factor: 17.088

Review 4.  Leigh and Leigh-like syndrome in children and adults.

Authors:  Josef Finsterer
Journal:  Pediatr Neurol       Date:  2008-10       Impact factor: 3.372

5.  Severe subacute necrotizing encephalopathy (Leigh-like syndrome) in American Staffordshire bull terrier dogs.

Authors:  D Collins; J M Angles; J Christodoulou; D Spielman; S A Lindsay; J Boyd; M B Krockenberger
Journal:  J Comp Pathol       Date:  2012-11-02       Impact factor: 1.311

6.  Alaskan Husky encephalopathy--a canine neurodegenerative disorder resembling subacute necrotizing encephalomyelopathy (Leigh syndrome).

Authors:  O Brenner; J J Wakshlag; B A Summers; A de Lahunta
Journal:  Acta Neuropathol       Date:  2000-07       Impact factor: 17.088

7.  Clinicopathologic and magnetic resonance imaging characteristics associated with polioencephalomyelopathy in a Shih Tzu.

Authors:  Marc Kent; Simon R Platt; Raquel R Rech; Dharshan Neravanda; Elizabeth W Uhl; Scott J Schatzberg
Journal:  J Am Vet Med Assoc       Date:  2009-09-01       Impact factor: 1.936

8.  Leigh-like subacute necrotising encephalopathy in Yorkshire Terriers: neuropathological characterisation, respiratory chain activities and mitochondrial DNA.

Authors:  Kerstin Baiker; Sabine Hofmann; Andrea Fischer; Thomas Gödde; Susanne Medl; Wolfgang Schmahl; Matthias F Bauer; Kaspar Matiasek
Journal:  Acta Neuropathol       Date:  2009-05-23       Impact factor: 17.088
  8 in total

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