Literature DB >> 25565473

Treating nonsuicidal self-injury: a systematic review of psychological and pharmacological interventions.

Brianna J Turner1, Sara B Austin1, Alexander L Chapman2.   

Abstract

OBJECTIVE: Nonsuicidal self-injury (NSSI), the deliberate, self-inflicted damage of bodily tissue without the intent to die, is associated with various negative outcomes. Although basic and epidemiologic research on NSSI has increased during the last 2 decades, literature on effective interventions targeting NSSI is still emerging. Here, we present a comprehensive, systematic review of existing psychological and pharmacological treatments designed specifically for NSSI, or including outcome assessments examining change in NSSI.
METHOD: We conducted a systematic search of PsycINFO, MEDLINE, and ERIC databases to retrieve relevant articles that met inclusion criteria; specifically, uncontrolled and controlled trials that 1) presented quantitative outcome data on NSSI, and 2) clearly differentiated NSSI from suicidal self-injury (SSI). Consistent with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, definition of NSSI, we excluded studies examining populations with developmental or intellectual disabilities, or with psychotic disorders.
RESULTS: Several interventions appear to hold promise for reducing NSSI, including dialectical behaviour therapy, emotion regulation group therapy, manual-assisted cognitive therapy, dynamic deconstructive psychotherapy, atypical antipsychotics (aripiprazole), naltrexone, and selective serotonin reuptake inhibitors (with or without cognitive-behavioural therapy). Nevertheless, there remains a paucity of well-controlled studies investigating treatment efficacy for NSSI.
CONCLUSIONS: Structured psychotherapeutic approaches focusing on collaborative therapeutic relationships, motivation for change, and directly addressing NSSI behaviours seem to be most effective in reducing NSSI. Medications targeting the serotonergic, dopaminergic and opioid systems also have demonstrated some benefits. Future studies employing controlled designs as well as a clear delineation of NSSI and SSI will improve knowledge regarding treatment effects.

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Year:  2014        PMID: 25565473      PMCID: PMC4244876          DOI: 10.1177/070674371405901103

Source DB:  PubMed          Journal:  Can J Psychiatry        ISSN: 0706-7437            Impact factor:   4.356


  83 in total

1.  Non-suicidal self-injury, attempted suicide, and suicidal intent among psychiatric inpatients.

Authors:  Margaret S Andover; Brandon E Gibb
Journal:  Psychiatry Res       Date:  2010-05-04       Impact factor: 3.222

2.  Buprenorphine in the treatment of non-suicidal self-injury: a case series and discussion of the literature.

Authors:  Lisa J Norelli; Howard S Smith; Leo Sher; Tracey A Blackwood
Journal:  Int J Adolesc Med Health       Date:  2013

3.  Non-suicidal self-injury among adolescents: diagnostic correlates and relation to suicide attempts.

Authors:  Matthew K Nock; Thomas E Joiner; Kathryn H Gordon; Elizabeth Lloyd-Richardson; Mitchell J Prinstein
Journal:  Psychiatry Res       Date:  2006-08-02       Impact factor: 3.222

4.  Manual assisted cognitive treatment for deliberate self-harm in borderline personality disorder patients.

Authors:  Igor Weinberg; John G Gunderson; John Hennen; Christopher J Cutter
Journal:  J Pers Disord       Date:  2006-10

5.  Brief dialectical behavior therapy (DBT-B) for suicidal behavior and non-suicidal self injury.

Authors:  Barbara Stanley; Beth Brodsky; Joshua D Nelson; Rebecca Dulit
Journal:  Arch Suicide Res       Date:  2007

6.  Dialectical behavior therapy skills use as a mediator and outcome of treatment for borderline personality disorder.

Authors:  Andrada D Neacsiu; Shireen L Rizvi; Marsha M Linehan
Journal:  Behav Res Ther       Date:  2010-05-23

7.  Adolescents with suicidal and nonsuicidal self-harm: clinical characteristics and response to therapeutic assessment.

Authors:  Dennis Ougrin; Tobias Zundel; Marinos Kyriakopoulos; Reetoo Banarsee; Daniel Stahl; Eric Taylor
Journal:  Psychol Assess       Date:  2011-08-22

8.  Reasons for suicide attempts and nonsuicidal self-injury in women with borderline personality disorder.

Authors:  Milton Z Brown; Katherine Anne Comtois; Marsha M Linehan
Journal:  J Abnorm Psychol       Date:  2002-02

9.  Naltrexone as a treatment for repetitive self-injurious behaviour:an open-label trial.

Authors:  A S Roth; R B Ostroff; R E Hoffman
Journal:  J Clin Psychiatry       Date:  1996-06       Impact factor: 4.384

10.  Predictors of spontaneous and systematically assessed suicidal adverse events in the treatment of SSRI-resistant depression in adolescents (TORDIA) study.

Authors:  David A Brent; Graham J Emslie; Greg N Clarke; Joan Asarnow; Anthony Spirito; Louise Ritz; Benedetto Vitiello; Satish Iyengar; Boris Birmaher; Neal D Ryan; Jamie Zelazny; Matthew Onorato; Betsy Kennard; Taryn L Mayes; Lynn L Debar; James T McCracken; Michael Strober; Robert Suddath; Henrietta Leonard; Giovanna Porta; Martin B Keller
Journal:  Am J Psychiatry       Date:  2009-02-17       Impact factor: 18.112

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  35 in total

1.  Nonsuicidal self-injury: what we know, and what we need to know.

Authors:  E David Klonsky; Sarah E Victor; Boaz Y Saffer
Journal:  Can J Psychiatry       Date:  2014-11       Impact factor: 4.356

2.  Non-Suicidal Self-Injury in Adolescence: Longitudinal Associations with Psychological Distress and Rumination.

Authors:  Tinne Buelens; Koen Luyckx; Amarendra Gandhi; Glenn Kiekens; Laurence Claes
Journal:  J Abnorm Child Psychol       Date:  2019-09

3.  Reciprocal Risk: the Longitudinal Relationship between Emotion Regulation and Non-suicidal Self-Injury in Adolescents.

Authors:  Kealagh Robinson; Jessica A Garisch; Tahlia Kingi; Madeleine Brocklesby; Angelique O'Connell; Robyn L Langlands; Lynne Russell; Marc S Wilson
Journal:  J Abnorm Child Psychol       Date:  2019-02

4.  Medications for Alcohol and Opioid Use Disorders and Risk of Suicidal Behavior, Accidental Overdoses, and Crime.

Authors:  Yasmina Molero; Johan Zetterqvist; Ingrid A Binswanger; Clara Hellner; Henrik Larsson; Seena Fazel
Journal:  Am J Psychiatry       Date:  2018-08-02       Impact factor: 18.112

5.  An intervention for nonsuicidal self-injury in young adults: A pilot randomized controlled trial.

Authors:  Margaret S Andover; Heather T Schatten; Blair W Morris; Caroline S Holman; Ivan W Miller
Journal:  J Consult Clin Psychol       Date:  2017-04-17

6.  A functional analysis of two transdiagnostic, emotion-focused interventions on nonsuicidal self-injury.

Authors:  Kate H Bentley; Matthew K Nock; Shannon Sauer-Zavala; Bernard S Gorman; David H Barlow
Journal:  J Consult Clin Psychol       Date:  2017-04-10

7.  Psychotropic drugs for the treatment of non-suicidal self-injury in children and adolescents: a systematic review and meta-analysis.

Authors:  Vincent Eggart; Sebastian Cordier; Alkomiet Hasan; Elias Wagner
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2022-02-16       Impact factor: 5.270

8.  Improvement of nonsuicidal self-injury following treatment with antipsychotics possessing strong D1 antagonistic activity: evidence from a report of three cases.

Authors:  Bastian Wollweber; Martin E Keck; Ulrike Schmidt
Journal:  Ther Adv Psychopharmacol       Date:  2015-08

9.  The role of interpersonal conflict and perceived social support in nonsuicidal self-injury in daily life.

Authors:  Brianna J Turner; Rebecca J Cobb; Kim L Gratz; Alexander L Chapman
Journal:  J Abnorm Psychol       Date:  2016-02-04

10.  Non-Suicidal Self-Injury Among Incarcerated Adolescents: Prevalence, Personality, and Psychiatric Comorbidity.

Authors:  Roman Koposov; Andrew Stickley; Vladislav Ruchkin
Journal:  Front Psychiatry       Date:  2021-05-19       Impact factor: 4.157

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