Literature DB >> 25565440

PLGA: a unique polymer for drug delivery.

Deepak N Kapoor1, Amit Bhatia, Ripandeep Kaur, Ruchi Sharma, Gurvinder Kaur, Sanju Dhawan.   

Abstract

Biodegradable polymers have played an important role in the delivery of drugs in a controlled and targeted manner. Polylactic-co-glycolic acid (PLGA) is one of the extensively researched synthetic biodegradable polymers due to its favorable properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive behavior. A wide range of PLGA-based drug delivery systems have been reported for the treatment or diagnosis of various diseases and disorders. The present review provides an overview of the chemistry, physicochemical properties, biodegradation behavior, evaluation parameters and applications of PLGA in drug delivery. Different drug-polymer combinations developed into drug delivery or carrier systems are enumerated and discussed.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 25565440     DOI: 10.4155/tde.14.91

Source DB:  PubMed          Journal:  Ther Deliv        ISSN: 2041-5990


  110 in total

Review 1.  Cardiovascular Bio-Engineering: Current State of the Art.

Authors:  Teresa Simon-Yarza; Isabelle Bataille; Didier Letourneur
Journal:  J Cardiovasc Transl Res       Date:  2017-03-06       Impact factor: 4.132

2.  Sequence-Controlled Polymers Through Entropy-Driven Ring-Opening Metathesis Polymerization: Theory, Molecular Weight Control, and Monomer Design.

Authors:  Jamie A Nowalk; Cheng Fang; Amy L Short; Ryan M Weiss; Jordan H Swisher; Peng Liu; Tara Y Meyer
Journal:  J Am Chem Soc       Date:  2019-03-27       Impact factor: 15.419

Review 3.  The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market.

Authors:  Ricardo Titze-de-Almeida; Catherine David; Simoneide Souza Titze-de-Almeida
Journal:  Pharm Res       Date:  2017-04-07       Impact factor: 4.200

Review 4.  Nanoparticles and nanofibers for topical drug delivery.

Authors:  Ritu Goyal; Lauren K Macri; Hilton M Kaplan; Joachim Kohn
Journal:  J Control Release       Date:  2015-10-28       Impact factor: 9.776

Review 5.  Three-dimensional Printing and 3D Slicer: Powerful Tools in Understanding and Treating Structural Lung Disease.

Authors:  George Z Cheng; Raul San Jose Estepar; Erik Folch; Jorge Onieva; Sidhu Gangadharan; Adnan Majid
Journal:  Chest       Date:  2016-03-12       Impact factor: 9.410

Review 6.  Advances and clinical challenges for translating nerve conduit technology from bench to bed side for peripheral nerve repair.

Authors:  Poonam Meena; Anupama Kakkar; Mukesh Kumar; Nitin Khatri; Rakesh Kumar Nagar; Aarti Singh; Poonam Malhotra; Manish Shukla; Sumit Kumar Saraswat; Supriya Srivastava; Rajan Datt; Siddharth Pandey
Journal:  Cell Tissue Res       Date:  2020-11-17       Impact factor: 5.249

Review 7.  [Nanoparticles as drug delivery systems in ophthalmology].

Authors:  M Löscher; J Hurst; L Strudel; M S Spitzer; S Schnichels
Journal:  Ophthalmologe       Date:  2018-03       Impact factor: 1.059

8.  Amphotericin B-loaded nanoparticles for local treatment of cutaneous leishmaniasis.

Authors:  Aiman Abu Ammar; Abed Nasereddin; Suheir Ereqat; Mary Dan-Goor; Charles L Jaffe; Eyal Zussman; Ziad Abdeen
Journal:  Drug Deliv Transl Res       Date:  2019-02       Impact factor: 4.617

9.  Hollow Microparticles as a Superior Delivery System over Solid Microparticles for the Encapsulation of Peptides.

Authors:  Sharad Kharel; Archana Gautam; Andreas Dickescheid; Say Chye Joachim Loo
Journal:  Pharm Res       Date:  2018-08-02       Impact factor: 4.200

Review 10.  Multifunctional nanomedicines for targeting epidermal growth factor receptor in colorectal cancer.

Authors:  Mostafa Akbarzadeh Khiavi; Azam Safary; Jaleh Barar; Amir Ajoolabady; Mohammad Hossein Somi; Yadollah Omidi
Journal:  Cell Mol Life Sci       Date:  2019-09-28       Impact factor: 9.261

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.