| Literature DB >> 25565440 |
Deepak N Kapoor1, Amit Bhatia, Ripandeep Kaur, Ruchi Sharma, Gurvinder Kaur, Sanju Dhawan.
Abstract
Biodegradable polymers have played an important role in the delivery of drugs in a controlled and targeted manner. Polylactic-co-glycolic acid (PLGA) is one of the extensively researched synthetic biodegradable polymers due to its favorable properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive behavior. A wide range of PLGA-based drug delivery systems have been reported for the treatment or diagnosis of various diseases and disorders. The present review provides an overview of the chemistry, physicochemical properties, biodegradation behavior, evaluation parameters and applications of PLGA in drug delivery. Different drug-polymer combinations developed into drug delivery or carrier systems are enumerated and discussed.Entities:
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Year: 2015 PMID: 25565440 DOI: 10.4155/tde.14.91
Source DB: PubMed Journal: Ther Deliv ISSN: 2041-5990