Literature DB >> 25565304

Economic Burden of Psoriasis in the United States: A Systematic Review.

Elizabeth A Brezinski1, Jaskaran S Dhillon1, April W Armstrong2.   

Abstract

IMPORTANCE: The total cost of psoriasis in the United States is unknown. Defining the US economic burden of psoriasis is needed because it provides the foundation for research, advocacy, and educational efforts.
OBJECTIVE: To determine the US economic burden of psoriasis from a societal perspective. EVIDENCE REVIEW: PubMed and MEDLINE databases were searched between January 1, 2008, and September 20, 2013, for economic investigations on the direct, indirect, intangible, and comorbidity costs of adult psoriasis in the United States. The base year costs were adjusted to 2013 US dollars using the Consumer Price Index for All Urban Consumers and multiplied by the estimated number of US patients with psoriasis in 2013 to determine the 2013 psoriasis cost burden.
FINDINGS: Among 100 identified articles, 22 studies were included in the systematic review. The direct psoriasis costs ranged from $51.7 billion to $63.2 billion, the indirect costs ranged from $23.9 billion to $35.4 billion, and medical comorbidities were estimated to contribute $36.4 billion annually in 2013 US dollars. Patients with psoriasis would pay a lifetime cost of $11,498 for relief of physical symptoms and emotional health; however, intangible cost data are limited. The annual US cost of psoriasis amounted to approximately $112 billion in 2013. CONCLUSIONS AND RELEVANCE: The economic burden of psoriasis is substantial and significant in the United States.

Entities:  

Mesh:

Year:  2015        PMID: 25565304     DOI: 10.1001/jamadermatol.2014.3593

Source DB:  PubMed          Journal:  JAMA Dermatol        ISSN: 2168-6068            Impact factor:   10.282


  47 in total

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2.  Racial Differences in Perceptions of Psoriasis Therapies: Implications for Racial Disparities in Psoriasis Treatment.

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3.  Inflammatory skin disorders and self-esteem.

Authors:  C Y Yang; A S Kourosh
Journal:  Int J Womens Dermatol       Date:  2017-10-21

4.  The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice.

Authors:  Nicholas J Geraghty; Kylie J Mansfield; Stephen J Fuller; Debbie Watson; Ronald Sluyter
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Authors:  Steven R Feldman; Bernard Goffe; Gary Rice; Matthew Mitchell; Mandeep Kaur; Debbie Robertson; Debra Sierka; Jeffrey A Bourret; Tamara S Evans; Alice Gottlieb
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6.  Initiation, Switching, and Cessation of Psoriasis Treatments Among Patients with Moderate to Severe Psoriasis in the United States.

Authors:  April W Armstrong; J Will Koning; Simon Rowse; Huaming Tan; Carla Mamolo; Mandeep Kaur
Journal:  Clin Drug Investig       Date:  2017-05       Impact factor: 2.859

7.  A Preliminary, Open Label, Single-arm Study of Calcipotriene/Betamethasone Topical Suspension as a Supplement to Non-biologic Systemic Therapy for Psoriasis.

Authors:  Laura Korb Ferris; Erine Kupetsky; Neil A M Houston
Journal:  J Clin Aesthet Dermatol       Date:  2016-04-01

Review 8.  Psoriasis pathogenesis and the development of novel targeted immune therapies.

Authors:  Jason E Hawkes; Tom C Chan; James G Krueger
Journal:  J Allergy Clin Immunol       Date:  2017-09       Impact factor: 10.793

9.  Loss of the Epigenetic Mark 5-hmC in Psoriasis: Implications for Epidermal Stem Cell Dysregulation.

Authors:  Feng Li; Christine W Yuan; Shuyun Xu; Tingjian Zu; Yvon Woappi; Catherine A A Lee; Phammela Abarzua; Michael Wells; Matthew R Ramsey; Natasha Y Frank; Xunwei Wu; Anna Mandinova; Markus H Frank; Christine G Lian; George F Murphy
Journal:  J Invest Dermatol       Date:  2019-12-11       Impact factor: 8.551

10.  Association between serum visfatin levels and psoriasis and their correlation with disease severity: a meta-analysis.

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Journal:  J Int Med Res       Date:  2021-03       Impact factor: 1.671

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