OBJECTIVES: The diagnostic role of endoscopic ultrasound (EUS) in children has only recently been demonstrated, and that also to a lesser extent than in adults. Data on the technique's therapeutic indications remain scarce. We therefore sought to evaluate diagnostic and interventional EUS indications, safety, and impact in children with pancreaticobiliary disorders. METHODS: We retrospectively reviewed our single pediatric center records, covering a 14-year period. RESULTS: From January 2000 to January 2014, 52 EUS procedures were performed in 48 children (mean age: 12 years; range: 2-17 years) with pancreaticobiliary disorders for the following indications: suspected biliary obstruction (n = 20/52), acute/chronic pancreatitis (n = 20), pancreatic mass (n = 3), pancreatic trauma (n = 7), and ampullary adenoma (n = 2). EUS was found to have a positive impact in 51 of 52 procedures, enabling us to avoid endoscopic retrograde cholangiopancreatography (ERCP) (n = 13 biliary; n = 6 pancreatic), focusing instead on endotherapy (n = 7 biliary; n = 14 pancreatic) or reorienting therapy toward surgery (n = 7). EUS-guided fine-needle aspiration was carried out on 12 patients for pancreatic tumor (n = 4), pancreatic cyst fluid analysis (n = 4), autoimmune pancreatitis (n = 2), and suspicion of biliary tumor (n = 2). A total of 13 therapeutic EUS procedures (11 children) were conducted, including 9 combined EUS-ERCP procedures (7 children, mean age: 8 years, range: 4-11 years), 3 EUS-guided pseudocyst drainage (2 children), and 1 EUS-guided transgastric biliary drainage. CONCLUSIONS: Our study reports on a large pediatric EUS series for diagnostic and therapeutic pancreaticobiliary disorders, demonstrating the impact of diagnostic EUS and affording insights into novel EUS and combined EUS-ERCP therapeutic applications. We suggest considering EUS as a diagnostic and therapeutic tool in the management of pediatric pancreaticobiliary diseases.
OBJECTIVES: The diagnostic role of endoscopic ultrasound (EUS) in children has only recently been demonstrated, and that also to a lesser extent than in adults. Data on the technique's therapeutic indications remain scarce. We therefore sought to evaluate diagnostic and interventional EUS indications, safety, and impact in children with pancreaticobiliary disorders. METHODS: We retrospectively reviewed our single pediatric center records, covering a 14-year period. RESULTS: From January 2000 to January 2014, 52 EUS procedures were performed in 48 children (mean age: 12 years; range: 2-17 years) with pancreaticobiliary disorders for the following indications: suspected biliary obstruction (n = 20/52), acute/chronic pancreatitis (n = 20), pancreatic mass (n = 3), pancreatic trauma (n = 7), and ampullary adenoma (n = 2). EUS was found to have a positive impact in 51 of 52 procedures, enabling us to avoid endoscopic retrograde cholangiopancreatography (ERCP) (n = 13 biliary; n = 6 pancreatic), focusing instead on endotherapy (n = 7 biliary; n = 14 pancreatic) or reorienting therapy toward surgery (n = 7). EUS-guided fine-needle aspiration was carried out on 12 patients for pancreatic tumor (n = 4), pancreatic cyst fluid analysis (n = 4), autoimmune pancreatitis (n = 2), and suspicion of biliary tumor (n = 2). A total of 13 therapeutic EUS procedures (11 children) were conducted, including 9 combined EUS-ERCP procedures (7 children, mean age: 8 years, range: 4-11 years), 3 EUS-guided pseudocyst drainage (2 children), and 1 EUS-guided transgastric biliary drainage. CONCLUSIONS: Our study reports on a large pediatric EUS series for diagnostic and therapeutic pancreaticobiliary disorders, demonstrating the impact of diagnostic EUS and affording insights into novel EUS and combined EUS-ERCP therapeutic applications. We suggest considering EUS as a diagnostic and therapeutic tool in the management of pediatric pancreaticobiliary diseases.
Authors: Isabelle Scheers; Joseph J Palermo; Steven Freedman; Michael Wilschanski; Uzma Shah; Maisam Abu-El-Haija; Bradley Barth; Douglas S Fishman; Cheryl Gariepy; Matthew J Giefer; Melvin B Heyman; Ryan W Himes; Sohail Z Husain; Tom K Lin; Quin Liu; Mark Lowe; Maria Mascarenhas; Veronique Morinville; Chee Y Ooi; Emily R Perito; David A Piccoli; John F Pohl; Sarah J Schwarzenberg; David Troendle; Steven Werlin; Bridget Zimmerman; Aliye Uc; Tanja Gonska Journal: Am J Gastroenterol Date: 2017-04-04 Impact factor: 10.864
Authors: Rafia Rashid; Md Samsul Arfin; A S M Bazlul Karim; Muhammad Baharul Alam; Salahuddin Mahmud Journal: Pediatr Gastroenterol Hepatol Nutr Date: 2022-07-06
Authors: Ramit Mahajan; Ebby George Simon; Ashok Chacko; D Viswanath Reddy; P Rupesh Kalyan; A J Joseph; Amit Kumar Dutta; Sudipta Dhar Chowdhury; Reuben Thomas Kurien Journal: Indian J Gastroenterol Date: 2016-03-05
Authors: Douglas S Fishman; Bruno P Chumpitazi; Isaac Raijman; Cynthia Man-Wai Tsai; E O'Brian Smith; Mark V Mazziotti; Mark A Gilger Journal: World J Gastrointest Endosc Date: 2016-06-10
Authors: Isabelle Scheers; Joseph J Palermo; Steven Freedman; Michael Wilschanski; Uzma Shah; Maisam Abu-El-Haija; Bradley Barth; Douglas S Fishman; Cheryl Gariepy; Matthew J Giefer; Melvin B Heyman; Ryan W Himes; Sohail Z Husain; Tom K Lin; Quin Liu; Mark Lowe; Maria Mascarenhas; Veronique Morinville; Chee Y Ooi; Emily R Perito; David A Piccoli; John F Pohl; Sarah J Schwarzenberg; David Troendle; Steven Werlin; Bridget Zimmerman; Aliye Uc; Tanja Gonska Journal: J Pediatr Gastroenterol Nutr Date: 2018-08 Impact factor: 2.839
Authors: Amit Raina; Maire A Conrad; Benjamin Sahn; Alireza Sedarat; Gregory G Ginsberg; Nuzhat A Ahmad; Vinay Chandrasekhara; Petar Mamula; Michael L Kochman Journal: Endosc Ultrasound Date: 2017 May-Jun Impact factor: 5.628