Ahti Anttila1, Arun Pokhrel, Pirjo Heikkilä, Riitta Viinanen, Eero Pukkala. 1. From the Finnish Cancer Registry (Drs Anttila, Pokhrel, and Pukkala), Institute for Statistical and Epidemiological Cancer Research, Unioninkatu 22; Finnish Institute of Occupational Health (Dr Heikkilä), Topeliuksenkatu 41aA, Helsinki; RV Chem Oy (Mr Viinanen), Ruoriniemenkatu 12, Lahti; and School of Health Sciences (Dr Pukkala), University of Tampere, Finland.
Abstract
OBJECTIVE: The purpose of this study was to assess whether occupational exposure to hydrocarbons in the oil-refining activity increases the risk of kidney cancer. METHODS: This case-referent study was nested within the cohort of employees in the oil refinery industry in Finland in 1967 to 1982 (n = 9454). The final data included 30 cases of kidney cancer and 81 age- and sex-matched referents. RESULTS: There was a threefold increase in the kidney cancer risk for exposure to hydrocarbons in crude oil (odds ratio, 3.1; confidence interval, 1.1 to 8.9; 11 exposed cases). The risk was associated with the highest cumulative exposure category to hydrocarbons in crude oil. CONCLUSIONS: Occupational exposure in oil refining, particularly to crude oil, may increase kidney cancer risk. The study assessed historical exposures; further information needs to be collected for evaluating current exposures.
OBJECTIVE: The purpose of this study was to assess whether occupational exposure to hydrocarbons in the oil-refining activity increases the risk of kidney cancer. METHODS: This case-referent study was nested within the cohort of employees in the oil refinery industry in Finland in 1967 to 1982 (n = 9454). The final data included 30 cases of kidney cancer and 81 age- and sex-matched referents. RESULTS: There was a threefold increase in the kidney cancer risk for exposure to hydrocarbons in crude oil (odds ratio, 3.1; confidence interval, 1.1 to 8.9; 11 exposed cases). The risk was associated with the highest cumulative exposure category to hydrocarbons in crude oil. CONCLUSIONS: Occupational exposure in oil refining, particularly to crude oil, may increase kidney cancer risk. The study assessed historical exposures; further information needs to be collected for evaluating current exposures.
Authors: Felix M Onyije; Bayan Hosseini; Kayo Togawa; Joachim Schüz; Ann Olsson Journal: Int J Environ Res Public Health Date: 2021-04-20 Impact factor: 3.390