Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications.

Imidazo[1,2-a]pyrazine acts as a versatile scaffold in organic synthesis and drug development. This review article is an effort to compile the progress made in synthetic methods and to illustrate its reactivity and multifarious biological activity. This review is mainly based on the pattern and position of the substitution, and should help the scientific community to bring about future developments.