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Literature DB >> 25562588

General last-step labeling of biomolecule-based substrates by [12C], [13C], and [11C] carbon monoxide.

Thomas Cornilleau¹, Hélène Audrain, Aude Guillemet, Philippe Hermange, Eric Fouquet.

Abstract

Alkaloid-, steroid-, biotin-, carbohydrate-, nucleoside-, and peptide-based bioconjugates are easily labeled with CO by a last-step palladium-catalyzed carbonylation. The choice of the [(12)C], [(13)C], or [(11)C] isotope opens the way to a new class of potential tracers or ligands easily available for various applications.

Entities: Chemical

Mesh：

Substances：

Year: 2015 PMID： 25562588 DOI： 10.1021/ol503471e

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

4 in total

1. Direct ¹¹CN-Labeling of Unprotected Peptides via Palladium-Mediated Sequential Cross-Coupling Reactions.

Authors: Wenjun Zhao; Hong Geun Lee; Stephen L Buchwald; Jacob M Hooker
Journal: J Am Chem Soc Date: 2017-05-17 Impact factor: 15.419

Review 2. Chemistry for Positron Emission Tomography: Recent Advances in ¹¹ C-, ¹⁸ F-, ¹³ N-, and ¹⁵ O-Labeling Reactions.

Authors: Xiaoyun Deng; Jian Rong; Lu Wang; Neil Vasdev; Lei Zhang; Lee Josephson; Steven H Liang
Journal: Angew Chem Int Ed Engl Date: 2019-01-14 Impact factor: 15.336

3. Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO₂.

Authors: Antonio Del Vecchio; Fabien Caillé; Arnaud Chevalier; Olivier Loreau; Kaisa Horkka; Christer Halldin; Magnus Schou; Nathalie Camus; Pascal Kessler; Bertrand Kuhnast; Frédéric Taran; Davide Audisio
Journal: Angew Chem Int Ed Engl Date: 2018-07-03 Impact factor: 15.336

Review 4. [¹¹C]Carbon monoxide: advances in production and application to PET radiotracer development over the past 15 years.

Authors: Carlotta Taddei; Victor W Pike
Journal: EJNMMI Radiopharm Chem Date: 2019-09-18

4 in total

General last-step labeling of biomolecule-based substrates by [12C], [13C], and [11C] carbon monoxide.

1. Direct 11CN-Labeling of Unprotected Peptides via Palladium-Mediated Sequential Cross-Coupling Reactions.

Review 2. Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions.

3. Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2.

Review 4. [11C]Carbon monoxide: advances in production and application to PET radiotracer development over the past 15 years.

1. Direct ¹¹CN-Labeling of Unprotected Peptides via Palladium-Mediated Sequential Cross-Coupling Reactions.

Review 2. Chemistry for Positron Emission Tomography: Recent Advances in ¹¹ C-, ¹⁸ F-, ¹³ N-, and ¹⁵ O-Labeling Reactions.

3. Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO₂.

Review 4. [¹¹C]Carbon monoxide: advances in production and application to PET radiotracer development over the past 15 years.