δ,ε-Unsaturated α,β-diamino acids as building blocks for the asymmetric synthesis of diverse α,β-diamino acids.

A building block approach for the synthesis of α,β-diamino acids is described, which involves the diastereodivergent preparation of two sets of orthogonally protected δ,ε-unsaturated α,β-diamino acids as templates for the preparation of 12 new α,β-diamino acids of biological relevance using simple techniques.