Literature DB >> 2556144

Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.

K Mitani1, H Fujita, S Sassa, A Kappas.   

Abstract

Heat shock treatment of human Hep 3B hepatoma cells led to the induction of mRNA for microsomal heme oxygenase. The maximum induction of heme oxygenase mRNA (5----7-fold) was observed with treatment of cells at 43.5 degrees C, for 60 min. The heat-mediated induction of heme oxygenase mRNA was blocked by simultaneous treatment of cells with actinomycin D or cycloheximide. In contrast to Hep 3B cells, cells of another human hepatoma line, Hep G2, showed little induction of heme oxygenase mRNA by heat treatment. These findings suggest that heat shock treatment induces heme oxygenase mRNA in certain human hepatoma cells, but not in others.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2556144     DOI： 10.1016/0006-291x(89)91089-9

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

Review 1.  Parasite heat-shock proteins and host responses: the balance between protection and immunopathology.

Authors:  D Mazier; D Mattei
Journal:  Springer Semin Immunopathol       Date:  1991

2.  Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs.

Authors:  S Quan; L Yang; N G Abraham; A Kappas
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-09       Impact factor: 11.205

3.  Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity.

Authors:  N G Abraham; Y Lavrovsky; M L Schwartzman; R A Stoltz; R D Levere; M E Gerritsen; S Shibahara; A Kappas
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205

4.  Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: evidence against a stress-mediated response.

Authors:  E E Cable; O S Gildemeister; J A Pepe; R W Lambrecht; H L Bonkovsky
Journal:  Mol Cell Biochem       Date:  1997-04       Impact factor: 3.396

5.  Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene.

Authors:  M Rizzardini; M Terao; F Falciani; L Cantoni
Journal:  Biochem J       Date:  1993-03-01       Impact factor: 3.857

Review 6.  Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders.

Authors:  P J Syapin
Journal:  Br J Pharmacol       Date:  2008-09-15       Impact factor: 8.739

7.  The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells.

Authors:  K Mitani; H Fujita; Y Fukuda; A Kappas; S Sassa
Journal:  Biochem J       Date:  1993-03-15       Impact factor: 3.857

8.  A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene.

Authors:  K Mitani; H Fujita; S Sassa; A Kappas
Journal:  Biochem J       Date:  1991-08-01       Impact factor: 3.857

9.  Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene.

Authors:  Y Lavrovsky; M L Schwartzman; R D Levere; A Kappas; N G Abraham
Journal:  Proc Natl Acad Sci U S A       Date:  1994-06-21       Impact factor: 11.205

10.  Induction by prostaglandin A1 of haem oxygenase in myoblastic cells: an effect independent of expression of the 70 kDa heat shock protein.

Authors:  A Rossi; M G Santoro
Journal:  Biochem J       Date:  1995-06-01       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.