Literature DB >> 2556122

Adrenocorticotropic hormone-releasing activities of interleukins in a homologous in vivo system.

Y Naito1, J Fukata, T Tominaga, Y Masui, Y Hirai, N Murakami, S Tamai, K Mori, H Imura.   

Abstract

We compared adrenocorticotropin-releasing activities of several interleukins in a homologous or heterologous in vivo system. Intravenous injection of rat interleukin-1 alpha significantly increased plasma adrenocorticotropin in conscious, freely-moving rats 30 min after the injection, and the effect was 10 times greater than that of human interleukin-1 alpha. Rat interleukin-2 affected plasma adrenocorticotropin in a much slower manner and increased its levels significantly 120 min after the injection. Human interleukin-2 had no effect on plasma adrenocorticotropin. Thus, species difference in the experimental system should be considered to assess the physiological significance of cytokines in the neuroendocrine system.

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Year:  1989        PMID： 2556122     DOI： 10.1016/0006-291x(89)91805-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

1.  The beneficial effects of treatment with tamoxifen and anti-oestradiol antibody on experimental systemic lupus erythematosus are associated with cytokine modulations.

Authors:  M Dayan; H Zinger; F Kalush; G Mor; Y Amir-Zaltzman; F Kohen; Z Sthoeger; E Mozes
Journal:  Immunology       Date:  1997-01       Impact factor: 7.397

Review 2.  Cytokines as mediators in the regulation of the hypothalamic-pituitary-adrenocortical function.

Authors:  J Fukata; H Imura; K Nakao
Journal:  J Endocrinol Invest       Date:  1994-02       Impact factor: 4.256

Review 3.  Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection.

Authors:  Marni N Silverman; Brad D Pearce; Christine A Biron; Andrew H Miller
Journal:  Viral Immunol       Date:  2005       Impact factor: 2.257

4.  Characterization of Interleukin-2 (IL-2) receptor expression and action of IL-2 and IL-6 on normal anterior pituitary cell growth.

Authors:  E Arzt; J Sauer; R Buric; J Stalla; U Renner; G K Stalla
Journal:  Endocrine       Date:  1995-02       Impact factor: 3.633

5.  Interleukin-2 affects steroidogenesis and numbers of bovine ovarian granulosa cells but not thecal cellsin vitro.

Authors:  C A Rajagopala Raja; L J Spicer; R E Stewart
Journal:  Endocrine       Date:  1995-12       Impact factor: 3.633

6.  Alteration of interleukin-1 alpha production and interleukin-1 alpha binding sites in mouse brain during rabies infection.

Authors:  C Marquette; P E Ceccaldi; E Ban; P Weber; H Tsiang; F Haour
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

7.  Interleukin-2 and interleukin-2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures.

Authors:  E Arzt; G Stelzer; U Renner; M Lange; O A Müller; G K Stalla
Journal:  J Clin Invest       Date:  1992-11       Impact factor: 14.808

8.  Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression.

Authors:  K Ye; K C Koch; B D Clark; C A Dinarello
Journal:  Immunology       Date:  1992-03       Impact factor: 7.397
  8 in total

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