| Literature DB >> 25559035 |
Bing Xu1, Shuang Liu, Xu-Dong Fan, Li-Qing Deng, Wen-Hui Ma, Min Chen.
Abstract
Phytochemical investigation on the seeds of Herpetospermum caudigerum afforded two new coumarin glycosides A and B (1 and 2), together with a known compound herpetolide A (3). Their structures were determined by spectroscopic methods, including 2D NMR techniques. Compound 3 exhibited cytotoxicity against HepG2 cells with IC50 value of 6.47 μg/ml. Compound 2 showed anti-hepatitis B virus activity with HBsAg secretion by 33.1% at 200 μg/ml.Entities:
Keywords: Herpetospermum caudigerum; coumarin glycoside; herpetosperin A; herpetosperin B
Mesh:
Substances:
Year: 2015 PMID: 25559035 DOI: 10.1080/10286020.2014.996137
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN: 1028-6020 Impact factor: 1.569