Literature DB >> 25557937

Introducing a Novel In Vitro Model to Characterize Hydrodynamic Effects of Percutaneous Nephrolithotomy Systems.

Rene Mager1, Christopher Balzereit2, Michael Reiter1, Kilian Gust1, Hendrik Borgmann1, Tanja Hüsch1, Udo Nagele3, Axel Haferkamp1, David Schilling1.   

Abstract

PURPOSE: To widen the understanding of the fluid mechanics during percutaneous nephrolithotomy (PCNL), a new in vitro model for empiric studies was developed. Our first aim was to characterize common PCNL systems with regard to their intrapyelocaliceal pressure and their irrigation flow volume as possible parameters of hydrodynamic invasiveness.
MATERIALS AND METHODS: The model is based on a watertight cylindrical cast. Low pressure miniaturized PCNL (miniPCNL) systems and conventional PCNL systems were tested. Intrapelvic pressure and the total of irrigation flow volume per minute were measured for each PCNL system at 10 predefined levels of irrigation pressure between 40 and 130 cm H2O.
RESULTS: Linear regression showed a linear relation between irrigation pressure and intrapelvic pressure. Compared with miniPCNL systems, conventional PCNL sheaths with closed Rutner sidearm generate significantly higher intrapelvic pressures. Opening the Rutner sidearm leads to a decrease in intrapelvic pressure to the level of the open mini PCNL systems. Polynomal regression revealed a square root relation between irrigation pressure and irrigation flow volume.
CONCLUSIONS: Our in vitro model is suitable for obtaining reliable and valid data of intrapelvic pressure and irrigation flow volume of commonly used PCNL systems. Conventional PCNL sheaths with opened Rutner sidearm provide intrapelvic pressure and irrigation volume similar to miniPCNL. Consequently, a relevant difference of the hydrodynamic impact between conventional and miniPCNL systems are not necessarily to be assumed. Regression analysis revealed a new starting point for further empiric research of fluid mechanics during PCNL.

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Year:  2015        PMID: 25557937     DOI: 10.1089/end.2014.0854

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  2 in total

1.  The hydrodynamic basis of the vacuum cleaner effect in continuous-flow PCNL instruments: an empiric approach and mathematical model.

Authors:  R Mager; C Balzereit; K Gust; T Hüsch; T Herrmann; U Nagele; A Haferkamp; D Schilling
Journal:  World J Urol       Date:  2015-09-10       Impact factor: 4.226

Review 2.  Pressure matters 2: intrarenal pressure ranges during upper-tract endourological procedures.

Authors:  Theodoros Tokas; Andreas Skolarikos; Thomas R W Herrmann; Udo Nagele
Journal:  World J Urol       Date:  2018-06-18       Impact factor: 4.226

  2 in total

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