Literature DB >> 2555750

Differential distribution of GABAA receptor mRNAs in bovine cerebellum--localization of alpha 2 mRNA in Bergmann glia layer.

W Wisden1, L A McNaughton, M G Darlison, S P Hunt, E A Barnard.   

Abstract

Using in situ hybridization histochemistry, we have demonstrated that 3 alpha subunit mRNAs of the GABAA receptor are present in different cell populations of the bovine cerebellum. While the alpha 1 mRNA is the most abundant and is present in granule cells, Purkinje cells and stellate/basket cells, the alpha 2 mRNA appears to be confined to the Bergmann glial cell layer. The alpha 3 mRNA is only expressed in the Golgi cells. This differential distribution of GABAA receptor mRNA subtypes suggests a previously unrecognized complexity of GABAergic transmission in the cerebellum.

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Year:  1989        PMID： 2555750     DOI： 10.1016/0304-3940(89)90193-6

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  8 in total

1.  Light and electron microscopic localization of GABAA-receptors on cultured cerebellar granule cells and astrocytes using immunohistochemical techniques.

Authors:  G H Hansen; E Hösli; B Belhage; A Schousboe; L Hösli
Journal:  Neurochem Res       Date:  1991-03       Impact factor: 3.996

2.  Expression of the γ2-subunit distinguishes synaptic and extrasynaptic GABA(A) receptors in NG2 cells of the hippocampus.

Authors:  Stefan Passlick; Michael Grauer; Christoph Schäfer; Ronald Jabs; Gerald Seifert; Christian Steinhäuser
Journal:  J Neurosci       Date:  2013-07-17       Impact factor: 6.167

3.  Immunohistochemical studies on the cellular localization of GABAA-receptors in explant cultures of rat central nervous system using a monoclonal antibody.

Authors:  E Hösli; L Hösli
Journal:  Exp Brain Res       Date:  1990       Impact factor: 1.972

Review 4.  Glutamate and GABA receptors in vertebrate glial cells.

Authors:  G von Blankenfeld; H Kettenmann
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

5.  Distribution of mRNA for the GABA transporter GAT-1 in the rat brain: evidence that GABA uptake is not limited to presynaptic neurons.

Authors:  M Swan; A Najlerahim; R E Watson; J P Bennett
Journal:  J Anat       Date:  1994-10       Impact factor: 2.610

6.  [3H]muscimol and [3H]flunitrazepam binding sites in the developing cerebellum of mice treated with methylazoxymethanol at different postnatal ages.

Authors:  E Bacon; C Girard; J de Barry; G Gombos
Journal:  Neurochem Res       Date:  1992-07       Impact factor: 3.996

7.  Muscimol and flunitrazepam binding sites in a subcellular fraction enriched in rat cerebellar glomeruli.

Authors:  F Viennot; B Foucaud; G Gombos
Journal:  Neurochem Res       Date:  1992-07       Impact factor: 3.996

8.  Molecular and synaptic organization of GABAA receptors in the cerebellum: Effects of targeted subunit gene deletions.

Authors:  Jean-Marc Fritschy; Patrizia Panzanelli
Journal:  Cerebellum       Date:  2006       Impact factor: 3.648
  8 in total

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