Literature DB >> 25556864

Ureteral stent insertion for gynecologic interstitial high-dose-rate brachytherapy.

D Jeffrey Demanes1, Robyn Banerjee2, Benjamin L Cahan2, Steve P Lee2, Sang-June Park2, Julia M Fallon2, Paula Reyes2, Thanh Q Van2, Michael L Steinberg2, Mitchell R Kamrava2.   

Abstract

PURPOSE: To determine the utility of ureteral stents in interstitial gynecological brachytherapy. METHODS AND MATERIALS: We reviewed 289 patients with cervix cancer treated with high-dose-rate interstitial brachytherapy who did not have pretreatment hydronephrosis to determine the relative incidence of benign ureteral strictures after treatment. We also did comparative dosimetry analysis in five cases of high-dose-rate brachytherapy. Bilateral ureteral stents were placed during the procedure. Three dosimetry plans were created to determine the impact of modifying clinical target volume (CTV) and applying ureteral dose constraints. In Plan 1, the ureters were contoured and excluded from the CTV and 120% dose constraints were applied. In Plan 2, the ureters were contoured and excluded, but no dose constraints were applied to the ureter. In Plan 3, the CTV was created as if the location of the ureters was unknown and then ureteral dose was determined.
RESULTS: There were 11 ureteral strictures observed in 255 nonstented cases and 0 ureteral strictures in 34 stented cases. Plan 1 reduced the ureter dose (D(0.1cc)) by a median 22% (7.0-53.8%) compared with Plan 2 and by a median of 30.9% (12.3-65%). compared with Plan 3.
CONCLUSIONS: Placement of stents and ureteral dose constraints facilitates dosimetry and reduces the dose to ureters. Temporary ureteral stents prevent obstruction during interstitial gynecologic brachytherapy and allows the ureters to be addressed as an organ at risk.
Copyright © 2015. Published by Elsevier Inc.

Entities:  

Keywords:  Brachytherapy; Cervix cancer; Endometrial cancer; Gynecologic malignancy; HDR; High-dose-rate; Interstitial; Stricture; Ureter; Ureteral stent

Mesh:

Year:  2014        PMID: 25556864     DOI: 10.1016/j.brachy.2014.11.013

Source DB:  PubMed          Journal:  Brachytherapy        ISSN: 1538-4721            Impact factor:   2.362


  3 in total

1.  Outcomes of Ureteroneocystostomy in Patients With Cancer.

Authors:  Gillian L Stearns; Amy L Tin; Nicole E Benfante; Daniel D Sjoberg; Jaspreet S Sandhu
Journal:  Urology       Date:  2021-09-06       Impact factor: 2.633

2.  Can preoperative ureteral stents reduce the incidence of ureteral stricture after radiotherapy in patients with cervical cancer?

Authors:  Liang Liu; Chunhong Yu; Fuzhen Sun; Tao Yang; Dong Wei; Gang Wang; Shoubin Li; Junjiang Liu
Journal:  BMC Urol       Date:  2022-07-18       Impact factor: 2.090

3.  Biodegradable Stent with mTOR Inhibitor-Eluting Reduces Progression of Ureteral Stricture.

Authors:  Dong-Ru Ho; Shih-Horng Su; Pey-Jium Chang; Wei-Yu Lin; Yun-Ching Huang; Jian-Hui Lin; Kuo-Tsai Huang; Wai-Nga Chan; Chih-Shou Chen
Journal:  Int J Mol Sci       Date:  2021-05-26       Impact factor: 5.923

  3 in total

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