Literature DB >> 25556563

Metastatic calcification of floor of the mouth secondary to chronic renal failure-report of a rare case with atypical presentation.

D K Verma1, Y Thelekkat, S Bansal.   

Abstract

Soft-tissue calcification is always pathological. Metastatic calcification is calcification of soft tissues owing to hyperphosphataemia with or without hypercalcaemia. Metastatic calcification of oral cavity is extremely rare. A case report of metastatic calcification of the floor of the mouth with atypical radiologic and clinical picture is presented here along with a review of earlier reports. A chance finding of the granular oral mucosa on palpation led to a radiographic examination revealing granular calcifications of the floor of the mouth. Blood chemistry and hormone analysis revealed chronic renal failure and hyperparathyroidism. A diagnosis of metastatic calcification secondary to renal failure was made and the treatment was aimed at correcting the renal failure without any intervention for the asymptomatic calcifications. Key differences between the present case and other cases reported in the literature are outlined.

Entities:  

Keywords:  calcinosis; chronic renal failure; hyperparathyroidism; oral metastatic calcification; pathological calcification

Mesh:

Year:  2015        PMID: 25556563      PMCID: PMC4628494          DOI: 10.1259/dmfr.20140023

Source DB:  PubMed          Journal:  Dentomaxillofac Radiol        ISSN: 0250-832X            Impact factor:   2.419


  9 in total

1.  A case of metastatic calcinosis of the oral cavity.

Authors:  H Yamada; K Seto; Y Matsumoto
Journal:  J Oral Maxillofac Surg       Date:  2000-03       Impact factor: 1.895

Review 2.  Metastatic calcification of the nasal septum presenting as an intraoral mass: a case report with a review of the literature.

Authors:  F Alawi; P D Freedman
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2001-06

3.  Soft tissue calcification in pediatric patients with end-stage renal disease.

Authors:  D S Milliner; A R Zinsmeister; E Lieberman; B Landing
Journal:  Kidney Int       Date:  1990-11       Impact factor: 10.612

Review 4.  Hypercalcemia and metastatic calcification.

Authors:  D N Kerr
Journal:  Cardiovasc Res       Date:  1997-12       Impact factor: 10.787

5.  Pathological calcifications associated with uremia: two types of calcium phosphate deposits.

Authors:  R Z LeGeros; S R Contiguglia; A C Alfrey
Journal:  Calcif Tissue Res       Date:  1973-10-23

6.  Metastatic calcification of the oral mucosa in renal hyperparathyroidism.

Authors:  M Shear; M Copelyn
Journal:  Br J Oral Surg       Date:  1966-11

7.  Metastatic soft tissue calcification presenting as a tongue mass.

Authors:  R P Walker; P D Kooiker; J M Chow; G W Sizemore; E Solans; E Paloyan; G J Kinzler
Journal:  Otolaryngol Head Neck Surg       Date:  1993-09       Impact factor: 3.497

8.  Oral presentation of metastatic calcinosis cutis.

Authors:  E E Omovie; E G Absi; C M Hill; A Ezsias; A J Potts
Journal:  Dentomaxillofac Radiol       Date:  1995-08       Impact factor: 2.419

Review 9.  The role of abnormal phosphorus metabolism in the progression of chronic kidney disease and metastatic calcification.

Authors:  Allen C Alfrey
Journal:  Kidney Int Suppl       Date:  2004-09       Impact factor: 10.545

  9 in total
  1 in total

1.  Dystrophic Calcification in the Oral Cavity Resulting in Mechanical Dysphagia: A Case Report and Review of Calcification in the Head and Neck Region.

Authors:  Anup Kumar G; Shakti Singh Deora
Journal:  Cureus       Date:  2020-03-30
  1 in total

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