Literature DB >> 25555881

Musculo-skeletal tumors incidence and surgical treatment - A single center 5-year retrospective.

J M Patrascu1, D Vermesan, M L Mioc, V Lazureanu, S Florescu, A Tarullo, M Tatullo, A Abbinante, M Caprio, R Cagiano, H Haragus.   

Abstract

OBJECTIVE: Muscle-skeletal tumors represent a challenging pathology for orthopedic surgeons worldwide. The extremely invasive character, the local destruction, the high recurrence rate, the high incidence in young patients and the unfavorable prognosis are all very well known. For these patients it is very important to produce an accelerated functional, social and psychological postoperative rehabilitation. We studied 121 cases of muscle-skeletal tumors which were treated in our hospital over a 5 years period. PATIENTS AND METHODS: We noticed a high prevalence in males and mainly between the 2nd-3rd and 5th-7th decades of their life. At our observation, most patients were suffering in advanced stages of malignant lesions.
RESULTS: We try to manage amputations below 5%, with a significant reduction in introducing reconstructive surgical methods as a choice of treatment (10 prostheses and 12 cases of filling with acrylic cement or bone substituent increased with internal fixation). In this way we could observe an unusual ratio between benign and malignant tumors, probably caused by the patient's lack of concern for minimal symptoms. The rural citizen's addressability towards the medical system is alarmingly low, due to the big gap existing from diagnosis to treatment.
CONCLUSIONS: There is still an hard effort to develop better reconstructive techniques for the treatment of muscle-skeletal tumors and more studies must be made in order to achieve this goal.

Entities:  

Mesh:

Year:  2014        PMID: 25555881

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  4 in total

1.  Case series of patients with pathological dyaphiseal fractures from metastatic bone disease.

Authors:  Dinu Vermesan; Radu Prejbeanu; Horia Haragus; Alis Dema; Manuel D Oprea; Diana Andrei; Dan V Poenaru; Marius Niculescu
Journal:  Int Orthop       Date:  2017-08-02       Impact factor: 3.075

2.  Are night-time voiding and lower urinary tract symptoms significant risk factors for hip fractures caused by falling during the night in male subjects?

Authors:  Bogdan Hogea; Razvan Bardan; Mihai Sandesc; Jenel Marian Patrascu; Alin Cumpanas; Bogdan Andor
Journal:  Patient Prefer Adherence       Date:  2019-07-22       Impact factor: 2.711

3.  Transferrin receptor-1 and VEGF are prognostic factors for osteosarcoma.

Authors:  Hongzeng Wu; Jinming Zhang; Ruoheng Dai; Jianfa Xu; Helin Feng
Journal:  J Orthop Surg Res       Date:  2019-09-04       Impact factor: 2.359

4.  Deep vein thrombosis following the treatment of lower limb pathologic bone fractures - a comparative study.

Authors:  Mihail-Lazar Mioc; Radu Prejbeanu; Dinu Vermesan; Horia Haragus; Marius Niculescu; Daniel Laurentiu Pop; Andrei Dan Balanescu; Daniel Malita; Bogdan Deleanu
Journal:  BMC Musculoskelet Disord       Date:  2018-07-11       Impact factor: 2.362

  4 in total

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