Luisa Nogueira1, Sofia Brandão2, Rita G Nunes3, Hugo Alexandre Ferreira3, Joana Loureiro2, Isabel Ramos4. 1. Department of Radiology, School of Health Technology of Porto/Polytechnic Institute of Porto (ESTSP/IPP), Rua Valente Perfeito, 4400-330, Vila Nova de Gaia, Portugal; Department of Radiology, Hospital de São João/Faculty of Medicine of Porto University (FMUP), Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal. Electronic address: mlpnogueira@med.up.pt. 2. MRI Unit, Department of Radiology, Hospital de São João, Alameda Prof. Hernani Monteiro, 4200-319 Porto, Portugal. 3. Institute of Biophysics and Biomedical Engineering (IBEB), Faculty of Sciences, University of Lisbon, Campo Grande, 1749-016, Lisboa, Portugal. 4. Department of Radiology, Hospital de São João/Faculty of Medicine of Porto University (FMUP), Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Abstract
AIM: To evaluate two fat-suppression techniques: short tau inversion recovery (STIR) and spectral adiabatic inversion recovery (SPAIR) regarding image quality and diagnostic performance in diffusion-weighted imaging (DWI) of breast lesions at 3 T. MATERIALS AND METHODS: Ninety-two women (mean age 48 ± 12.1 years; range 21-78 years) underwent breast MRI. Two DWI pulse sequences, with b-values (50 and 1000 s/mm(2)) were performed with STIR and SPAIR. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), suppression homogeneity, and apparent diffusion coefficient (ADC) values were quantitatively assessed for each technique. Values were compared between techniques and lesion type. Receiver operating characteristics (ROC) analysis was used to evaluate lesion discrimination. RESULTS: One hundred and fourteen lesions were analysed (40 benign and 74 malignant). SNR and CNR were significantly higher for DWI-SPAIR; fat-suppression uniformity was better for DWI-STIR (p < 1 × 10(-4)). ADC values for benign and malignant lesions and normal tissue were 1.92 × 10(-3), 1.18 × 10(-3), 1.86 × 10(-3) s/mm(2) for DWI-STIR and 1.80 × 10(-3), 1.11 × 10(-3), 1.79 × 10(-3) s/mm(2) for SPAIR, respectively. Comparison between fat-suppression techniques showed significant differences in mean ADC values for benign (p = 0.013) and malignant lesions (p = 0.001). DWI-STIR and -SPAIR ADC cut-offs were 1.42 × 10(-3) and 1.46 × 10(-3) s/mm(2), respectively. Diagnostic performance for DWI-STIR versus SPAIR was: accuracy (81.6 versus 83.3%), area under curve (87.7 versus 89.2%), sensitivity (79.7 versus 85.1%), and specificity (85 versus 80%). Positive predictive value was similar. CONCLUSION: The fat-saturation technique used in the present study may influence image quality and ADC quantification. Nevertheless, STIR and SPAIR techniques showed similar diagnostic performances, and therefore, both are suitable for use in clinical practice.
AIM: To evaluate two fat-suppression techniques: short tau inversion recovery (STIR) and spectral adiabatic inversion recovery (SPAIR) regarding image quality and diagnostic performance in diffusion-weighted imaging (DWI) of breast lesions at 3 T. MATERIALS AND METHODS: Ninety-two women (mean age 48 ± 12.1 years; range 21-78 years) underwent breast MRI. Two DWI pulse sequences, with b-values (50 and 1000 s/mm(2)) were performed with STIR and SPAIR. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), suppression homogeneity, and apparent diffusion coefficient (ADC) values were quantitatively assessed for each technique. Values were compared between techniques and lesion type. Receiver operating characteristics (ROC) analysis was used to evaluate lesion discrimination. RESULTS: One hundred and fourteen lesions were analysed (40 benign and 74 malignant). SNR and CNR were significantly higher for DWI-SPAIR; fat-suppression uniformity was better for DWI-STIR (p < 1 × 10(-4)). ADC values for benign and malignant lesions and normal tissue were 1.92 × 10(-3), 1.18 × 10(-3), 1.86 × 10(-3) s/mm(2) for DWI-STIR and 1.80 × 10(-3), 1.11 × 10(-3), 1.79 × 10(-3) s/mm(2) for SPAIR, respectively. Comparison between fat-suppression techniques showed significant differences in mean ADC values for benign (p = 0.013) and malignant lesions (p = 0.001). DWI-STIR and -SPAIR ADC cut-offs were 1.42 × 10(-3) and 1.46 × 10(-3) s/mm(2), respectively. Diagnostic performance for DWI-STIR versus SPAIR was: accuracy (81.6 versus 83.3%), area under curve (87.7 versus 89.2%), sensitivity (79.7 versus 85.1%), and specificity (85 versus 80%). Positive predictive value was similar. CONCLUSION: The fat-saturation technique used in the present study may influence image quality and ADC quantification. Nevertheless, STIR and SPAIR techniques showed similar diagnostic performances, and therefore, both are suitable for use in clinical practice.
Authors: S Gruber; L Minarikova; K Pinker; O Zaric; M Chmelik; B Strasser; P Baltzer; T Helbich; S Trattnig; W Bogner Journal: Eur Radiol Date: 2015-08-27 Impact factor: 5.315
Authors: K Deike-Hofmann; T Kuder; F König; D Paech; C Dreher; S Delorme; H-P Schlemmer; S Bickelhaupt Journal: Radiologe Date: 2018-11 Impact factor: 0.635
Authors: Ana E Rodríguez-Soto; Maren M Sjaastad Andreassen; Lauren K Fang; Christopher C Conlin; Helen H Park; Grace S Ahn; Hauke Bartsch; Joshua Kuperman; Igor Vidić; Haydee Ojeda-Fournier; Anne M Wallace; Michael Hahn; Tyler M Seibert; Neil Peter Jerome; Agnes Østlie; Tone Frost Bathen; Pål Erik Goa; Rebecca Rakow-Penner; Anders M Dale Journal: Magn Reson Med Date: 2021-12-14 Impact factor: 3.737