Literature DB >> 25555057

Ultrafast dynamic computed tomography myelography for the precise identification of high-flow cerebrospinal fluid leaks caused by spiculated spinal osteophytes.

Kent R Thielen1, John C Sillery, Jonathan M Morris, Joseph M Hoxworth, Felix E Diehn, John T Wald, Richard E Rosebrock, Lifeng Yu, Patrick H Luetmer.   

Abstract

OBJECT: Precise localization and understanding of the origin of spontaneous high-flow spinal CSF leaks is required prior to targeted treatment. This study demonstrates the utility of ultrafast dynamic CT myelography for the precise localization of high-flow CSF leaks caused by spiculated spinal osteophytes.
METHODS: This study reports a series of 14 patients with high-flow CSF leaks caused by spiculated spinal osteophytes who underwent ultrafast dynamic CT myelography between March 2009 and December 2010. There were 10 male and 4 female patients, with an average age of 49 years (range 37-74 years). The value of ultrafast dynamic CT myelography in depicting the CSF leak site was qualitatively assessed.
RESULTS: In all 14 patients, ultrafast dynamic CT myelography was technically successful at precisely demonstrating the site of the CSF leak, the causative spiculated osteophyte piercing the dura, and the relationship of the implicated osteophyte to adjacent structures. Leak sites included 3 cervical, 11 thoracic, and 0 lumbar levels, with 86% of the leaks occurring from C-5 to T-7. Information obtained from the ultrafast dynamic CT myelogram was considered useful in all treated CSF leaks.
CONCLUSIONS: Spinal osteophytes piercing the dura are a more frequent cause of high-flow CSF leaks than previously recognized. Ultrafast dynamic CT myelography adds value beyond standard dynamic myelography or digital subtraction myelography in the diagnosis and anatomical characterization of high-flow spinal CSF leaks caused by these osteophytes. This information allows for appropriate planning for percutaneous or surgical treatment.

Entities:  

Keywords:  DS = digital subtraction; cerebrospinal fluid leak; disc protrusion; headache; low pressure; osteophyte; technique

Mesh:

Year:  2015        PMID: 25555057     DOI: 10.3171/2014.10.SPINE14209

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  14 in total

1.  Spontaneous Intracranial Hypotension: A Systematic Imaging Approach for CSF Leak Localization and Management Based on MRI and Digital Subtraction Myelography.

Authors:  R I Farb; P J Nicholson; P W Peng; E M Massicotte; C Lay; T Krings; K G terBrugge
Journal:  AJNR Am J Neuroradiol       Date:  2019-03-28       Impact factor: 3.825

2.  Penetrating Osseous Spicules Causing High-Flow Ventral CSF Leaks in the Setting of Relatively Low BMI : A Preliminary Study.

Authors:  Richard E Rosebrock; Felix E Diehn; Patrick H Luetmer; John T Wald; John I Lane; Jonathan M Morris; Vance T Lehman; Carrie M Carr; Bahram Mokri; Kent R Thielen
Journal:  Clin Neuroradiol       Date:  2017-05-16       Impact factor: 3.649

Review 3.  Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension.

Authors:  Peter G Kranz; Michael D Malinzak; Timothy J Amrhein; Linda Gray
Journal:  Curr Pain Headache Rep       Date:  2017-08

4.  Spinal CSF venous fistula: A treatable etiology for CSF leaks in craniospinal hypovolemia.

Authors:  Neeraj Kumar; Felix E Diehn; Carrie M Carr; Jared T Verdoorn; Ivan Garza; Patrick H Luetmer; John L D Atkinson; Jonathan M Morris
Journal:  Neurology       Date:  2016-05-13       Impact factor: 9.910

5.  CT and MR myelography in superficial siderosis.

Authors:  Nicola Morelli; Eugenia Rota; Paolo Immovilli; Giuseppe Marchesi; Emanuele Michieletti; Donata Guidetti
Journal:  Neurol Sci       Date:  2018-02-10       Impact factor: 3.307

Review 6.  CSF-Venous Fistula.

Authors:  Michelle Roytman; Gayle Salama; Matthew S Robbins; J Levi Chazen
Journal:  Curr Pain Headache Rep       Date:  2021-01-21

7.  Diagnostic yield of MR myelography in patients with newly diagnosed spontaneous intracranial hypotension: a systematic review and meta-analysis.

Authors:  So Jeong Lee; Dana Kim; Chong Hyun Suh; Hwon Heo; Woo Hyun Shim; Sang Joon Kim
Journal:  Eur Radiol       Date:  2022-05-11       Impact factor: 5.315

Review 8.  Diskogenic Dural Defect Is the Reason for the Ventral Location of the Epidural Spinal Fluid Collection Seen in Superficial Siderosis.

Authors:  Neeraj Kumar
Journal:  Neurol Clin Pract       Date:  2021-08

9.  Application of time-spatial labeling inversion pulse magnetic resonance imaging in the diagnosis of spontaneous intracranial hypotension due to high-flow cerebrospinal fluid leakage at C1-2.

Authors:  Natsuki Hattori; Joji Inamasu; Shunsuke Nakae; Yuichi Hirose; Kazuhiro Murayama
Journal:  Surg Neurol Int       Date:  2016-12-26

10.  Spontaneous intracranial hypotension in a patient with systemic lupus erythematosus.

Authors:  Dan Isaac Cohen-Addad; Aslan Efendizade; Arkadij Grigorian; Kevin Hewitt; Vinodkumar Velayudhan
Journal:  Radiol Case Rep       Date:  2019-08-01
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