Literature DB >> 25554860

In vivo analysis of biodegradable liposome gold nanoparticles as efficient agents for photothermal therapy of cancer.

Aravind Kumar Rengan1, Amirali B Bukhari, Arpan Pradhan, Renu Malhotra, Rinti Banerjee, Rohit Srivastava, Abhijit De.   

Abstract

We report biodegradable plasmon resonant liposome gold nanoparticles (LiposAu NPs) capable of killing cancer cells through photothermal therapy. The pharmacokinetic study of LiposAu NPs performed in a small animal model indicates in situ degradation in hepatocytes and further getting cleared through the hepato-biliary and renal route. Further, the therapeutic potential of LiposAu NPs tested in mouse tumor xenograft model using NIR laser (750 nm) illumination resulted in complete ablation of the tumor mass, thus prolonging disease-free survival.

Entities:  

Keywords:  Gold nanoparticles; cancer nanotechnology; liposomes; photothermal therapy; theranostics

Mesh：

Substances：

Year:  2015        PMID： 25554860     DOI： 10.1021/nl5045378

Source DB:  PubMed          Journal:  Nano Lett        ISSN： 1530-6984            Impact factor:   11.189


  47 in total

Review 1.  Hybrid lipid-nanoparticle complexes for biomedical applications.

Authors:  Kevin M Vargas; Young-Seok Shon
Journal:  J Mater Chem B       Date:  2019-01-03       Impact factor: 6.331

Review 2.  Current Status and Future Direction of Nanomedicine: Focus on Advanced Biological and Medical Applications.

Authors:  Eun-Mi Kim; Hwan-Jeong Jeong
Journal:  Nucl Med Mol Imaging       Date:  2016-08-09

3.  Biodegradable Gold Nanoclusters with Improved Excretion Due to pH-Triggered Hydrophobic-to-Hydrophilic Transition.

Authors:  Elizabeth M Higbee-Dempsey; Ahmad Amirshaghaghi; Matthew J Case; Mathilde Bouché; Johoon Kim; David P Cormode; Andrew Tsourkas
Journal:  J Am Chem Soc       Date:  2020-04-21       Impact factor: 15.419

4.  Advanced Functional Nanomaterials for Theranostics.

Authors:  Haoyuan Huang; Jonathan F Lovell
Journal:  Adv Funct Mater       Date:  2016-11-07       Impact factor: 18.808

5.  Degradable Hollow Mesoporous Silicon/Carbon Nanoparticles for Photoacoustic Imaging-Guided Highly Effective Chemo-Thermal Tumor Therapy in Vitro and in Vivo.

Authors:  Jinfeng Zhang; Jun Zhang; Wenyue Li; Rui Chen; Zhenyu Zhang; Wenjun Zhang; Yongbing Tang; Xiaoyuan Chen; Gang Liu; Chun-Sing Lee
Journal:  Theranostics       Date:  2017-07-22       Impact factor: 11.556

Review 6.  Carbon nanotubes as anti-bacterial agents.

Authors:  Teodora Mocan; Cristian T Matea; Teodora Pop; Ofelia Mosteanu; Anca Dana Buzoianu; Soimita Suciu; Cosmin Puia; Claudiu Zdrehus; Cornel Iancu; Lucian Mocan
Journal:  Cell Mol Life Sci       Date:  2017-05-23       Impact factor: 9.261

Review 7.  Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update.

Authors:  Saravanan Govindaraju; Kyusik Yun
Journal:  3 Biotech       Date:  2018-02-05       Impact factor: 2.406

Review 8.  Nanoparticles in Daily Life: Applications, Toxicity and Regulations.

Authors:  Ritu Gupta; Huan Xie
Journal:  J Environ Pathol Toxicol Oncol       Date:  2018       Impact factor: 3.567

Review 9.  What is new in nanoparticle-based photoacoustic imaging?

Authors:  Jeanne E Lemaster; Jesse V Jokerst
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2016-04-01

Review 10.  Physical stimuli-responsive vesicles in drug delivery: Beyond liposomes and polymersomes.

Authors:  Ulrike Kauscher; Margaret N Holme; Mattias Björnmalm; Molly M Stevens
Journal:  Adv Drug Deliv Rev       Date:  2018-10-25       Impact factor: 15.470
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