Richard J Santen1, Laurence M Demers2, Regina G Ziegler3. 1. Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health Sciences System, Charlottesville, VA, United States. 2. Departments of Pathology and Medicine, Pennsylvania State University School of Medicine, Hershey, PA, United States. 3. Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States.