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Literature DB >> 25554446

AATF RNome has the potential to define post mortem interval.

Abstract

Keeping in view the fact that the circadian rhythm governs human behavioral characteristics, metabolism and body function, the present study was directed to explore whether or not there exists any cooperativity between AATF RNome (comprising AATF mRNA and its encoded microRNA miR-2909) rhythmicity and post mortem interval (PMI). Such a study unambiguously revealed that circadian rhythm exhibited by AATF RNome has a direct correlation with PMI in Balb/c mice. AATF RNome has the potential to act as biomarker for PMI with reasonably good accuracy and hence may turn out to be of crucial importance in forensic investigation.

Entities: Gene Species

Keywords: AATF RNome; Circadian pacemaker; Expressional stability; PMI

Mesh：

Substances：

Year: 2014 PMID： 25554446 DOI： 10.1016/j.forsciint.2014.12.008

Source DB: PubMed Journal: Forensic Sci Int ISSN： 0379-0738 Impact factor: 2.395

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Cited

6 in total

AATF RNome has the potential to define post mortem interval.

Review 1. Analysis of RNA in the estimation of post-mortem interval: a review of current evidence.

2. Identification of potential genes and miRNAs associated with sepsis based on microarray analysis.

Review 3. MicroRNAs as Useful Tools to Estimate Time Since Death. A Systematic Review of Current Literature.

4. Quantitative analysis of noncoding RNA from paired fresh and formalin-fixed paraffin-embedded brain tissues.

5. Pleural fluid accumulation detectable on paediatric post-mortem imaging: a possible marker of interval since death?

6. Human cellular mitochondrial remodelling is governed by miR-2909 RNomics.