Literature DB >> 25553460

Poly-ADP-ribosylation signaling during DNA damage repair.

Barbara Golia1, Hari R Singh1, Gyula Timinszky1.   

Abstract

Poly-ADP-ribosylation is a post-translational modification generated in high amounts by poly-ADP-ribose polymerases (PARPs) in response to cellular stress, especially genotoxic stimuli. DNA damage-induced PARylation significantly changes local chromatin structure and triggers the accumulation of several DNA damage response (DDR) proteins at the DNA lesions. In this review, we will discuss the regulation of chromatin structure and DNA damage repair machineries by DNA damage-induced poly-ADP-ribosylation.

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Year:  2015        PMID： 25553460     DOI： 10.2741/4318

Source DB:  PubMed          Journal:  Front Biosci (Landmark Ed)        ISSN： 2768-6698


  10 in total

1.  Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function.

Authors:  Felix Y Feng; Johann S de Bono; Mark A Rubin; Karen E Knudsen
Journal:  Mol Cell       Date:  2015-06-18       Impact factor: 17.970

Review 2.  Autophagy in DNA damage response.

Authors:  Piotr Czarny; Elzbieta Pawlowska; Jolanta Bialkowska-Warzecha; Kai Kaarniranta; Janusz Blasiak
Journal:  Int J Mol Sci       Date:  2015-01-23       Impact factor: 5.923

3.  Disruption of Macrodomain Protein SCO6735 Increases Antibiotic Production in Streptomyces coelicolor.

Authors:  Jasna Lalić; Melanija Posavec Marjanović; Luca Palazzo; Dragutin Perina; Igor Sabljić; Roko Žaja; Thomas Colby; Bruna Pleše; Mirna Halasz; Gytis Jankevicius; Giselda Bucca; Marijan Ahel; Ivan Matić; Helena Ćetković; Marija Luić; Andreja Mikoč; Ivan Ahel
Journal:  J Biol Chem       Date:  2016-09-15       Impact factor: 5.157

4.  ATM induces MacroD2 nuclear export upon DNA damage.

Authors:  Barbara Golia; Giuliana Katharina Moeller; Gytis Jankevicius; Andreas Schmidt; Anna Hegele; Julia Preißer; Mai Ly Tran; Axel Imhof; Gyula Timinszky
Journal:  Nucleic Acids Res       Date:  2016-10-07       Impact factor: 16.971

Review 5.  The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore.

Authors:  Hagai Rottenberg; Jan B Hoek
Journal:  Aging Cell       Date:  2017-07-31       Impact factor: 9.304

6.  Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro.

Authors:  Xiaorong Mao; Senrong Du; Zhongxia Yang; Liting Zhang; Xuebin Peng; Ni Jiang; Haiyu Zhou
Journal:  Mol Med Rep       Date:  2017-05-10       Impact factor: 2.952

7.  Poly(ADP-ribosyl)ation associated changes in CTCF-chromatin binding and gene expression in breast cells.

Authors:  Ioanna Pavlaki; France Docquier; Igor Chernukhin; Georgia Kita; Svetlana Gretton; Christopher T Clarkson; Vladimir B Teif; Elena Klenova
Journal:  Biochim Biophys Acta Gene Regul Mech       Date:  2018-07-05       Impact factor: 4.490

Review 8.  Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors.

Authors:  Isabella Faraoni; Grazia Graziani
Journal:  Cancers (Basel)       Date:  2018-12-04       Impact factor: 6.639

Review 9.  Targeting the Mitochondrial Permeability Transition Pore to Prevent Age-Associated Cell Damage and Neurodegeneration.

Authors:  Andrew C Kent; Khairat Bahgat Youssef El Baradie; Mark W Hamrick
Journal:  Oxid Med Cell Longev       Date:  2021-01-28       Impact factor: 6.543

Review 10.  Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress.

Authors:  Stefania Pellegrino; Matthias Altmeyer
Journal:  Front Genet       Date:  2016-04-19       Impact factor: 4.599
  10 in total

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