Literature DB >> 25553163

A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome.

Dean A Tripp1, J Curtis Nickel2, Laura Katz3, Adrijana Krsmanovic3, Mark A Ware4, Darcy Santor5.   

Abstract

INTRODUCTION: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic pelvic pain condition largely refractory to treatment. Cannabis (marijuana) use has been reported for a wide variety of chronic pain conditions, but no study has examined prevalence of cannabis use, symptom benefit or side effects, or frequency in CP/CPPS.
METHODS: Participants were recruited from an outpatient CP/CPPS urology clinic (n = 98) and online through the Prostatitis Foundation website (n = 244). Participants completed questionnaires (demographics, CP/CPPS, depression, cannabis).
RESULTS: The clinic sample included Canadian patients and the online sample included primarily American patients. Due to differences, groups were examined separately. Almost 50% of respondents reported using cannabis (clinic n = 49; online n = 89). Of the cannabis users, 36.8% of clinic and 75% of online respondents reported that it improved their symptoms. Most of the respondents (from the clinic and online groups) reported that cannabis improved their mood, pain, muscle spasms, and sleep. However, they did not note any improvements for weakness, fatigue, numbness, ambulation, and urination. Overall, the effectiveness of cannabis for CP/CPPS was "somewhat/very effective" (57% clinic; 63% online). There were no differences between side effects or choice of consumption and most reported using cannabis rarely.
CONCLUSIONS: These are the first estimates in men suffering from CP/CPPS and suggest that while cannabis use is prevalent, its medical use and benefit are unknown. This is an understudied area and the benefit or hazard for cannabis use awaits further study.

Entities:  

Year:  2014        PMID: 25553163      PMCID: PMC4277530          DOI: 10.5489/cuaj.2268

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  23 in total

1.  Opioids for chronic prostatitis and interstitial cystitis: lessons learned from the 11th World Congress on Pain.

Authors:  J Curtis Nickel
Journal:  Urology       Date:  2006-10       Impact factor: 2.649

2.  The medicinal use of cannabis and cannabinoids--an international cross-sectional survey on administration forms.

Authors:  Arno Hazekamp; Mark A Ware; Kirsten R Muller-Vahl; Donald Abrams; Franjo Grotenhermen
Journal:  J Psychoactive Drugs       Date:  2013 Jul-Aug

Review 3.  Cannabinergic pain medicine: a concise clinical primer and survey of randomized-controlled trial results.

Authors:  Sunil K Aggarwal
Journal:  Clin J Pain       Date:  2013-02       Impact factor: 3.442

4.  Cannabinoid-opioid interaction in chronic pain.

Authors:  D I Abrams; P Couey; S B Shade; M E Kelly; N L Benowitz
Journal:  Clin Pharmacol Ther       Date:  2011-11-02       Impact factor: 6.875

5.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire.

Authors:  R L Spitzer; K Kroenke; J B Williams
Journal:  JAMA       Date:  1999-11-10       Impact factor: 56.272

Review 6.  Chronic pelvic pains represent the most prominent urogenital symptoms of "chronic prostatitis".

Authors:  J N Krieger; K J Egan; S O Ross; R Jacobs; R E Berger
Journal:  Urology       Date:  1996-11       Impact factor: 2.649

7.  The association of abuse and symptoms suggestive of chronic prostatitis/chronic pelvic pain syndrome: results from the Boston Area Community Health survey.

Authors:  Jim C Hu; Carol L Link; Mary McNaughton-Collins; Michael J Barry; John B McKinlay
Journal:  J Gen Intern Med       Date:  2007-09-01       Impact factor: 5.128

Review 8.  Management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): the studies, the evidence, and the impact.

Authors:  J Curtis Nickel; Daniel A Shoskes; Florian M E Wagenlehner
Journal:  World J Urol       Date:  2013-04-09       Impact factor: 4.226

9.  Prevalence, symptom impact and predictors of chronic prostatitis-like symptoms in Canadian males aged 16-19 years.

Authors:  Dean A Tripp; J Curtis Nickel; Stephanie Ross; Chris Mullins; Natalie Stechyson
Journal:  BJU Int       Date:  2008-10-24       Impact factor: 5.588

10.  Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.

Authors:  Wei Xiong; Tanxing Cui; Kejun Cheng; Fei Yang; Shao-Rui Chen; Dan Willenbring; Yun Guan; Hui-Lin Pan; Ke Ren; Yan Xu; Li Zhang
Journal:  J Exp Med       Date:  2012-05-14       Impact factor: 14.307

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  5 in total

Review 1.  Medical marijuana for urologic chronic pelvic pain.

Authors:  J Curtis Nickel
Journal:  Can Urol Assoc J       Date:  2018-06       Impact factor: 1.862

2.  CUA guideline: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome.

Authors:  Ashley Cox; Nicole Golda; Genevieve Nadeau; J Curtis Nickel; Lesley Carr; Jacques Corcos; Joel Teichman
Journal:  Can Urol Assoc J       Date:  2016-05-12       Impact factor: 1.862

3.  The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model.

Authors:  Longsheng Deng; Xikui Zhang; Weikun Zhu; Taikun Lu; Jinchun Chen; Qiang Zou; Qizhong Zheng; Junying Chen; Changming Jiang; Guanyu Jin
Journal:  Evid Based Complement Alternat Med       Date:  2017-12-21       Impact factor: 2.629

Review 4.  Recent advances in managing chronic prostatitis/chronic pelvic pain syndrome.

Authors:  Jaspreet Sandhu; Hin Yu Vincent Tu
Journal:  F1000Res       Date:  2017-09-25

5.  Using the UPOINT system to manage men with chronic pelvic pain syndrome.

Authors:  Darren J Bryk; Daniel A Shoskes
Journal:  Arab J Urol       Date:  2021-07-23
  5 in total

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