Literature DB >> 25552723

Parainfluenza virus 5 expressing the G protein of rabies virus protects mice after rabies virus infection.

Ying Huang1, Zhenhai Chen2, Junhua Huang1, ZhenFang Fu3, Biao He4.   

Abstract

Rabies remains a major public health threat around the world. Once symptoms appear, there is no effective treatment to prevent death. In this work, we tested a recombinant parainfluenza virus 5 (PIV5) strain expressing the glycoprotein (G) of rabies (PIV5-G) as a therapy for rabies virus infection: we have found that PIV5-G protected mice as late as 6 days after rabies virus infection. PIV5-G is a promising vaccine for prevention and treatment of rabies virus infection.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25552723      PMCID： PMC4337528          DOI： 10.1128/JVI.03656-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

1.  The serological response of young dogs to the Flury LEP strain of rabies virus vaccine.

Authors:  H O Aghomo; O O Oduye; C E Rupprecht
Journal:  Vet Res Commun       Date:  1990       Impact factor: 2.459

2.  Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge.

Authors:  S Mark Tompkins; Yuan Lin; George P Leser; Kari A Kramer; Debra L Haas; Elizabeth W Howerth; Jie Xu; Mary J Kennett; Russell K Durbin; Joan E Durbin; Ralph Tripp; Robert A Lamb; Biao He
Journal:  Virology       Date:  2007-01-23       Impact factor: 3.616

3.  Recovery of infectious SV5 from cloned DNA and expression of a foreign gene.

Authors:  B He; R G Paterson; C D Ward; R A Lamb
Journal:  Virology       Date:  1997-10-27       Impact factor: 3.616

4.  A respiratory syncytial virus (RSV) vaccine based on parainfluenza virus 5 (PIV5).

Authors:  Shannon I Phan; Zhenhai Chen; Pei Xu; Zhuo Li; Xiudan Gao; Stephanie L Foster; Michael N Teng; Ralph A Tripp; Kaori Sakamoto; Biao He
Journal:  Vaccine       Date:  2014-04-08       Impact factor: 3.641

5.  Rabies virus expressing dendritic cell-activating molecules enhances the innate and adaptive immune response to vaccination.

Authors:  Yongjun Wen; Hualei Wang; Hua Wu; Fuhe Yang; Ralph A Tripp; Robert J Hogan; Zhen F Fu
Journal:  J Virol       Date:  2010-11-24       Impact factor: 5.103

6.  Enhancement of blood-brain barrier permeability and reduction of tight junction protein expression are modulated by chemokines/cytokines induced by rabies virus infection.

Authors:  Qingqing Chai; Wen Q He; Ming Zhou; Huijun Lu; Zhen F Fu
Journal:  J Virol       Date:  2014-02-12       Impact factor: 5.103

7.  Recombinant parainfluenza virus 5 expressing hemagglutinin of influenza A virus H5N1 protected mice against lethal highly pathogenic avian influenza virus H5N1 challenge.

Authors:  Zhuo Li; Alaina J Mooney; Jon D Gabbard; Xiudan Gao; Pei Xu; Ryan J Place; Robert J Hogan; S Mark Tompkins; Biao He
Journal:  J Virol       Date:  2012-10-17       Impact factor: 5.103

8.  Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus.

Authors:  Milosz Faber; Jianwei Li; Rhonda B Kean; D Craig Hooper; Kishore R Alugupalli; Bernhard Dietzschold
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-06       Impact factor: 11.205

9.  A novel rabies vaccine based on a recombinant parainfluenza virus 5 expressing rabies virus glycoprotein.

Authors:  Zhenhai Chen; Ming Zhou; Xiudan Gao; Guoqing Zhang; Guiping Ren; Clement W Gnanadurai; Zhen F Fu; Biao He
Journal:  J Virol       Date:  2012-12-26       Impact factor: 5.103

10.  Intracerebral administration of recombinant rabies virus expressing GM-CSF prevents the development of rabies after infection with street virus.

Authors:  Hualei Wang; Guoqing Zhang; Yongjun Wen; Songtao Yang; Xianzhu Xia; Zhen F Fu
Journal:  PLoS One       Date:  2011-09-28       Impact factor: 3.240
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  3 in total

1.  A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV Challenge.

Authors:  Dai Wang; Shannon Phan; Daniel J DiStefano; Michael P Citron; Cheryl L Callahan; Lani Indrawati; Sheri A Dubey; Gwendolyn J Heidecker; Dhanasekaran Govindarajan; Xiaoping Liang; Biao He; Amy S Espeseth
Journal:  J Virol       Date:  2017-05-12       Impact factor: 5.103

Review 2.  Rabies Control and Treatment: From Prophylaxis to Strategies with Curative Potential.

Authors:  Shimao Zhu; Caiping Guo
Journal:  Viruses       Date:  2016-10-28       Impact factor: 5.048

Review 3.  Parainfluenza virus 5-vectored vaccines against human and animal infectious diseases.

Authors:  Zhenhai Chen
Journal:  Rev Med Virol       Date:  2018-01-05       Impact factor: 6.989
  3 in total

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