| Literature DB >> 25552503 |
N Ye Maksimovich1, I K Dremza1, E I Troian1, Ya N Maksimovich1, A N Borodinskiĭ1.
Abstract
The dynamics of changes in the mitochondrial respiratory function, changes in the parameters of carbohydrate metabolism and some parameters of oxidative stress in the brain tissue have been investigated under conditions of ischemia-reperfusion and administration of dihydroquercetin. Dihydroquercetin (65 mg/kg) was administered per os 1 h before modeling of ischemia-reperfusion. Studies were carried 1 h after reperfusion. It was found that administration of dihydroquercetin caused a corrective effect to impairments of the respiratory function of mitochondria, indicators of carbohydrate metabolism and parameters of oxidative stress induced by ischemia-reperfusion.Entities:
Keywords: brain; dihydroquercetin; mitochondrial respiration; oxidative stress; reperfusion
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Year: 2014 PMID： 25552503 DOI： 10.18097/pbmc20146006643
Source DB: PubMed Journal: Biomed Khim ISSN： 2310-6905