Literature DB >> 2555225

Human Na+,K+-ATPase genes. Beta-subunit gene family contains at least one gene and one pseudogene.

G S Monastyrskaya, N E Broude, N N Nikiforova, D A Bessarab, K E Petrukhin, N N Modyanov, E D Sverdlov.   

Abstract

The existence of a chromosome gene family containing at least one gene and one pseudogene was shown for the Na+,K+-ATPase beta-subunit. A partial structure of the beta 1-gene was determined, the coding part of which was completely homologous to cDNA of the Na+,K+-ATPase beta I-subunit from HeLa cells. The region encoding the putative protein transmembrane domain was shown to be bordered by two introns. The structure of a pseudogene (beta psi) was determined. This pseudogene is processed and contains multiple stop codons. Its homology to the beta I-subunit cDNA from HeLa cells is about 88%.

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Year:  1989        PMID: 2555225     DOI: 10.1016/0014-5793(89)81591-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  2 in total

Review 1.  The genes of Na,K-ATPase, a selfreview.

Authors:  E D Sverdlov
Journal:  Genetica       Date:  1991       Impact factor: 1.082

2.  Na,K-ATPase subunit isoforms in human reticulocytes: evidence from reverse transcription-PCR for the presence of alpha1, alpha3, beta2, beta3, and gamma.

Authors:  M K Stengelin; J F Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-27       Impact factor: 11.205

  2 in total

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