Literature DB >> 25549969

Autism cornered: network analyses reveal mechanisms of autism spectrum disorders.

Charles Auffray1.   

Abstract

Despite a wealth of behavioral, cognitive,biological, and genetic studies, the causes of autism have remained largely unknown.In their recent work, Snyder and colleagues(Li et al, 2014) use a systems biology approach and shed light on the molecular and cellular mechanisms underlying autism, thus opening novel avenues forunderstanding the disease and developing potential treatments.

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Mesh：

Year:  2014        PMID： 25549969      PMCID： PMC4300496          DOI： 10.15252/msb.20145937

Source DB:  PubMed          Journal:  Mol Syst Biol        ISSN： 1744-4292            Impact factor:   11.429


  9 in total

Review 1.  Boosting signal-to-noise in complex biology: prior knowledge is power.

Authors:  Trey Ideker; Janusz Dutkowski; Leroy Hood
Journal:  Cell       Date:  2011-03-18       Impact factor: 41.582

Review 2.  Autism spectrum disorders: from genes to neurobiology.

Authors:  A Jeremy Willsey; Matthew W State
Journal:  Curr Opin Neurobiol       Date:  2014-11-28       Impact factor: 6.627

3.  Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism.

Authors:  Neelroop N Parikshak; Rui Luo; Alice Zhang; Hyejung Won; Jennifer K Lowe; Vijayendran Chandran; Steve Horvath; Daniel H Geschwind
Journal:  Cell       Date:  2013-11-21       Impact factor: 41.582

4.  A systems biology approach identifies molecular networks defining skeletal muscle abnormalities in chronic obstructive pulmonary disease.

Authors:  Nil Turan; Susana Kalko; Anna Stincone; Kim Clarke; Ayesha Sabah; Katherine Howlett; S John Curnow; Diego A Rodriguez; Marta Cascante; Laura O'Neill; Stuart Egginton; Josep Roca; Francesco Falciani
Journal:  PLoS Comput Biol       Date:  2011-09-01       Impact factor: 4.475

Review 5.  The pathophysiology of autism.

Authors:  Pamela J Compart
Journal:  Glob Adv Health Med       Date:  2013-11

6.  The discovery of integrated gene networks for autism and related disorders.

Authors:  Fereydoun Hormozdiari; Osnat Penn; Elhanan Borenstein; Evan E Eichler
Journal:  Genome Res       Date:  2014-11-05       Impact factor: 9.043

7.  Integrated systems analysis reveals a molecular network underlying autism spectrum disorders.

Authors:  Jingjing Li; Minyi Shi; Zhihai Ma; Shuchun Zhao; Ghia Euskirchen; Jennifer Ziskin; Alexander Urban; Joachim Hallmayer; Michael Snyder
Journal:  Mol Syst Biol       Date:  2014-12-30       Impact factor: 11.429

8.  Modules, networks and systems medicine for understanding disease and aiding diagnosis.

Authors:  Mika Gustafsson; Colm E Nestor; Huan Zhang; Albert-László Barabási; Sergio Baranzini; Sören Brunak; Kian Fan Chung; Howard J Federoff; Anne-Claude Gavin; Richard R Meehan; Paola Picotti; Miguel Àngel Pujana; Nikolaus Rajewsky; Kenneth Gc Smith; Peter J Sterk; Pablo Villoslada; Mikael Benson
Journal:  Genome Med       Date:  2014-10-17       Impact factor: 11.117

9.  Network-based classification of breast cancer metastasis.

Authors:  Han-Yu Chuang; Eunjung Lee; Yu-Tsueng Liu; Doheon Lee; Trey Ideker
Journal:  Mol Syst Biol       Date:  2007-10-16       Impact factor: 11.429
  9 in total
  1 in total

1.  Fundamental challenges for autism research: the science-practice gap, demarcating autism and the unsuccessful search for the neurobiological basis of autism.

Authors:  Berend Verhoeff
Journal:  Med Health Care Philos       Date:  2015-08
  1 in total

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