Literature DB >> 25549586

Cancer: mTOR inhibition curbs colorectal cancer.

Sarah Crunkhorn.   

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Year:  2015        PMID： 25549586     DOI： 10.1038/nrd4523

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  1 in total

1.  mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.

Authors:  Thomas J Jackson; John Rp Knight; William J Faller; Rachel A Ridgway; Thomas Jamieson; Saadia A Karim; Carolyn Jones; Sorina Radulescu; David J Huels; Kevin B Myant; Kate M Dudek; Helen A Casey; Alessandro Scopelliti; Julia B Cordero; Marcos Vidal; Mario Pende; Alexey G Ryazanov; Nahum Sonenberg; Oded Meyuhas; Michael N Hall; Martin Bushell; Anne E Willis; Owen J Sansom
Journal:  Nature       Date:  2014-11-05       Impact factor: 49.962
  1 in total
  4 in total

1.  SAV1 represses the development of human colorectal cancer by regulating the Akt-mTOR pathway in a YAP-dependent manner.

Authors:  Jianwu Jiang; Wei Chang; Yang Fu; Yongshun Gao; Chunlin Zhao; Xiefu Zhang; Shuijun Zhang
Journal:  Cell Prolif       Date:  2017-06-15       Impact factor: 6.831

2.  Nrf2-miR-129-3p-mTOR Axis Controls an miRNA Regulatory Network Involved in HDACi-Induced Autophagy.

Authors:  Weijian Sun; Yongdong Yi; Guojun Xia; Yaxin Zhao; Yaojun Yu; Liyi Li; Chunya Hua; Bin He; Beng Yang; Chengyang Yu; Chenmin Ye; Fuyang Tu; Canjin Chen; Xiaoying Xu; Zhiqiang Zheng; Wenqian Wang; Xian Shen
Journal:  Mol Ther       Date:  2019-02-15       Impact factor: 11.454

Review 3.  The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials.

Authors:  Cian O Malley; Graham P Pidgeon
Journal:  BBA Clin       Date:  2015-11-12

4.  Dual Targeting by Inhibition of Phosphoinositide-3-Kinase and Mammalian Target of Rapamycin Attenuates the Neuroinflammatory Responses in Murine Hippocampal Cells and Seizures in C57BL/6 Mice.

Authors:  Preeti Vyas; Rajkumar Tulsawani; Divya Vohora
Journal:  Front Immunol       Date:  2021-11-23       Impact factor: 7.561
  4 in total

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