Tammie Ferringer1. 1. From the Departments of Dermatology and Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania.
Abstract
CONTEXT: Immunohistochemistry is not a diagnostic test but a highly valuable tool that requires interpretation within a context. OBJECTIVE: To review the current status and limitations of immunohistochemistry in dermatopathology. DATA SOURCES: English-language literature published between 1980 and 2014. CONCLUSIONS: Although immunohistochemistry is rarely completely specific or sensitive, it is an important adjunctive technique in dermatopathology and can be helpful in a series of diagnostic dilemmas.
CONTEXT: Immunohistochemistry is not a diagnostic test but a highly valuable tool that requires interpretation within a context. OBJECTIVE: To review the current status and limitations of immunohistochemistry in dermatopathology. DATA SOURCES: English-language literature published between 1980 and 2014. CONCLUSIONS: Although immunohistochemistry is rarely completely specific or sensitive, it is an important adjunctive technique in dermatopathology and can be helpful in a series of diagnostic dilemmas.