Literature DB >> 25546047

Surgically avertable burden of obstetric conditions in low- and middle-income regions: a modelled analysis.

H Higashi1, J J Barendregt, N J Kassebaum, T G Weiser, S W Bickler, T Vos.   

Abstract

OBJECTIVE: To quantify the burden of maternal and neonatal conditions in low- and middle-income countries (LMICs) that could be averted by full access to quality first-level obstetric surgical procedures.
DESIGN: Burden of disease and epidemiological modelling.
SETTING: LMICs from all global regions. POPULATION: The entire population in 2010.
METHODS: We included five conditions in our analysis: maternal haemorrhage; obstructed labour; obstetric fistula; abortion(1) ; and neonatal encephalopathy. Demographic and epidemiological data were obtained from the Global Burden of Disease 2010 study. We split the disability-adjusted life years (DALYs) of these conditions into surgically 'avertable' and 'non-avertable' burdens. We applied the lowest age-specific fatality rates from all global regions to each LMIC region to estimate the avertable deaths, assuming that the differences of death rates between each region and the lowest rates reflect the gap in surgical care. MAIN OUTCOME MEASURES: Deaths and DALYs avertable.
RESULTS: Of the estimated 56.6 million DALYs (i.e. 56.6 million years of healthy life lost) of the selected five conditions, 21.1 million DALYs (37%) are avertable by full coverage of quality obstetric surgery in LMICs. The avertable burden in absolute term is substantial given the size of burden of these conditions in LMICs. Neonatal encephalopathy constitutes the largest portion of avertable burden (16.2 million DALYs) among the five conditions, followed by abortion (2.1 million DALYs).
CONCLUSIONS: Improving access to quality surgical care at first-level hospitals could reduce a tremendous burden of maternal and neonatal conditions in LMICs.
© 2014 Royal College of Obstetricians and Gynaecologists.

Entities:  

Keywords:  Burden of disease; maternal conditions; neonatal conditions; obstetrics; surgery

Mesh:

Year:  2015        PMID: 25546047     DOI: 10.1111/1471-0528.13198

Source DB:  PubMed          Journal:  BJOG        ISSN: 1470-0328            Impact factor:   6.531


  13 in total

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2.  Access to Cesarean Section Will Reduce Maternal Mortality in Low-Income Countries: A Mathematical Model.

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3.  Association between parity and fistula location in women with obstetric fistula: a multivariate regression analysis.

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Review 8.  Urogenital fistula reviewed: a marker of severe maternal morbidity and an indicator of the quality of maternal healthcare delivery.

Authors:  Margo S Harrison; Hillary Mabeya; Robert L Goldenberg; Elizabeth M McClure
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9.  Improving Surgical and Anaesthesia Practice: Review of the Use of the WHO Safe Surgery Checklist in Felege Hiwot Referral Hospital, Ethiopia.

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10.  Risk factors for vaginal fistula symptoms in Sub-Saharan Africa: a pooled analysis of national household survey data.

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Journal:  BMC Pregnancy Childbirth       Date:  2016-04-21       Impact factor: 3.007

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