Literature DB >> 25544781

Neurological and psychiatric disorders as a neuroglial failure.

Alexei Verkhratsky1, Vladimir Parpura2.   

Abstract

Neuroglia are a diverse non-neuronal population of cells in the central and peripheral nervous system. These cells have a variety of functions that can all be summed up as the maintenance of homeostasis of the nervous system. It is the loss of homeostasis that represents the culprit of all disorders. Thus, neuroglia can be envisioned as the pivotal element in all neural disorders, be that neurological or psychiatric. In this review, we discuss the role of glia in homeostasis and defence of the nervous system as well as changes in the morpho-functional characteristics of these cells in various disorders.

Entities:  

Keywords:  NG2 glia; astrocyte; microglia; neurodegeneration; neuroglia; neurological diseases; oligodendrocyte; psychiatric diseases; reactive gliosis

Year:  2014        PMID: 25544781      PMCID: PMC4276339     

Source DB:  PubMed          Journal:  Period Biol        ISSN: 0031-5362            Impact factor:   0.313


  95 in total

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Review 2.  Astroglia in dementia and Alzheimer's disease.

Authors:  J J Rodríguez; M Olabarria; A Chvatal; A Verkhratsky
Journal:  Cell Death Differ       Date:  2008-12-05       Impact factor: 15.828

Review 3.  Physiology of microglia.

Authors:  Helmut Kettenmann; Uwe-Karsten Hanisch; Mami Noda; Alexei Verkhratsky
Journal:  Physiol Rev       Date:  2011-04       Impact factor: 37.312

4.  Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease.

Authors:  Markel Olabarria; Harun N Noristani; Alexei Verkhratsky; José J Rodríguez
Journal:  Glia       Date:  2010-05       Impact factor: 7.452

5.  The NG2 antigen, a putative lineage marker: immunofluorescent localization in primary cultures of rat brain.

Authors:  W B Stallcup
Journal:  Dev Biol       Date:  1981-04-15       Impact factor: 3.582

Review 6.  Astrocytes in Alzheimer's disease.

Authors:  Alexei Verkhratsky; Markel Olabarria; Harun N Noristani; Chia-Yu Yeh; Jose Julio Rodriguez
Journal:  Neurotherapeutics       Date:  2010-10       Impact factor: 7.620

7.  Aluminum-induced degeneration of astrocytes occurs via apoptosis and results in neuronal death.

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Journal:  Brain Res       Date:  1999-07-24       Impact factor: 3.252

8.  Alexander disease.

Authors:  Albee Messing; Michael Brenner; Mel B Feany; Maiken Nedergaard; James E Goldman
Journal:  J Neurosci       Date:  2012-04-11       Impact factor: 6.167

Review 9.  The glial perspective of autism spectrum disorders.

Authors:  Fares Zeidán-Chuliá; Alla B Salmina; Natalia A Malinovskaya; Mami Noda; Alexei Verkhratsky; José Cláudio Fonseca Moreira
Journal:  Neurosci Biobehav Rev       Date:  2013-12-01       Impact factor: 8.989

10.  Microglial response to Alzheimer's disease is differentially modulated by voluntary wheel running and enriched environments.

Authors:  J J Rodríguez; H N Noristani; A Verkhratsky
Journal:  Brain Struct Funct       Date:  2013-12-29       Impact factor: 3.270

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  7 in total

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2.  The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure.

Authors:  Herbert Renz-Polster; Marie-Eve Tremblay; Dorothee Bienzle; Joachim E Fischer
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3.  Three-Dimensional Environment Sustains Morphological Heterogeneity and Promotes Phenotypic Progression During Astrocyte Development.

Authors:  Swarnalatha Balasubramanian; John A Packard; Jennie B Leach; Elizabeth M Powell
Journal:  Tissue Eng Part A       Date:  2016-06       Impact factor: 3.845

Review 4.  Astrocyte heterogeneity in the brain: from development to disease.

Authors:  Clarissa Schitine; Luciana Nogaroli; Marcos R Costa; Cecilia Hedin-Pereira
Journal:  Front Cell Neurosci       Date:  2015-03-20       Impact factor: 5.505

Review 5.  Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders.

Authors:  Tuomo Mäki-Marttunen; Tobias Kaufmann; Torbjørn Elvsåshagen; Anna Devor; Srdjan Djurovic; Lars T Westlye; Marja-Leena Linne; Marcella Rietschel; Dirk Schubert; Stefan Borgwardt; Magdalena Efrim-Budisteanu; Francesco Bettella; Geir Halnes; Espen Hagen; Solveig Næss; Torbjørn V Ness; Torgeir Moberget; Christoph Metzner; Andrew G Edwards; Marianne Fyhn; Anders M Dale; Gaute T Einevoll; Ole A Andreassen
Journal:  Front Psychiatry       Date:  2019-08-06       Impact factor: 4.157

Review 6.  The Astrogenic Balance in the Aging Brain.

Authors:  Fotis Andromidas; Saeid Atashpanjeh; Abigail J Myers; Brooke E MacKinnon; Melanie M Shaffer; Andrew O Koob
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.708

7.  Validating indicators of CNS disorders in a swine model of neurological disease.

Authors:  Vicki J Swier; Katherine A White; David K Meyerholz; Aude Chefdeville; Rajesh Khanna; Jessica C Sieren; Dawn E Quelle; Jill M Weimer
Journal:  PLoS One       Date:  2020-02-19       Impact factor: 3.752

  7 in total

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