| Literature DB >> 25544781 |
Alexei Verkhratsky1, Vladimir Parpura2.
Abstract
Neuroglia are a diverse non-neuronal population of cells in the central and peripheral nervous system. These cells have a variety of functions that can all be summed up as the maintenance of homeostasis of the nervous system. It is the loss of homeostasis that represents the culprit of all disorders. Thus, neuroglia can be envisioned as the pivotal element in all neural disorders, be that neurological or psychiatric. In this review, we discuss the role of glia in homeostasis and defence of the nervous system as well as changes in the morpho-functional characteristics of these cells in various disorders.Entities:
Keywords: NG2 glia; astrocyte; microglia; neurodegeneration; neuroglia; neurological diseases; oligodendrocyte; psychiatric diseases; reactive gliosis
Year: 2014 PMID: 25544781 PMCID: PMC4276339
Source DB: PubMed Journal: Period Biol ISSN: 0031-5362 Impact factor: 0.313