Literature DB >> 25544173

[Associations of blood pressure, glucose or lipids with stroke in different age or gender].

Aiqun Zhu1, Jingping Zhang, Ting Zou, Guangzhong Xiong.   

Abstract

OBJECTIVE: To investigate the relationship between blood pressure, blood glucose or blood lipids and patients with cerebral infarction (CI) or intracerebral hemorrhage (ICH) in different age or gender.
METHODS: Th e case-control study consecutively recruited patients with fi rst-ever-in-a-lifetime CI (n=358) and ICH (n=230) and community-acquired pneumonia (n=165) as controls between January 2010 and December 2013 at the Second Xiangya Hospital of Central South University. The patients with CI or ICH were divided into the young group, the middle-aged group and the older group, and the risk factors were compared between the 3 groups. The patients with CI or ICH were respectively further divided into the male group and the female group. The blood pressure, glucose and lipids were measured.
RESULTS: Data from logistic regression models showed that CI was closely associated with high blood pressure, hypertension, diabetes mellitus (DM) or fasting plasma glucose (FPG) (P< 0.05), and ICH was closely related to high blood pressure, hypertension, low density lipoproteincholesterol (LDL-C), FPG, serum creatinine (SCr) or alcohol drinking (P< 0.05); hypertension was the main risk factor for stroke. The odds ratios for the young, the middle-aged and older group were 10.43, 4.74 and 7.39 respectively (P< 0.05). Systolic blood pressure (OR=28.74) was the important risk factor for the young stroke, and the OR is 2.81 for the middle-aged stroke. Diastolic blood pressure (OR=2.96) and DM (OR=6.25) were the risk factor for the middle-aged stroke. LDL-C (OR=2.87) was a risk factor for the older stroke; the mean levels of diastolic blood pressure in males were significantly increased compared with that in females with CI, while the mean levels of TC, HDL-C or LDL-C in females were significantly higher than that in males with ICH (P< 0.05).
CONCLUSION: Hypertension, systolic blood pressure in particular, is the most common risk factor for young stroke patients. DM and hypertension are the risk factors for the middle-aged patients, while hypertension, DM, LDL-C and alcohol consuming are the risk factors for the aged patients.

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Year:  2014        PMID: 25544173     DOI: 10.11817/j.issn.1672-7347.2014.12.009

Source DB:  PubMed          Journal:  Zhong Nan Da Xue Xue Bao Yi Xue Ban        ISSN: 1672-7347


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