Izaias Pereira da Costa1, Adriana B Bortoluzzo2, Célio R Gonçalves3, José Antonio Braga da Silva4, Antonio Carlos Ximenes5, Manoel B Bértolo6, Sandra L E Ribeiro7, Mauro Keiserman8, Rita Menin9, Thelma L Skare10, Sueli Carneiro11, Valderílio F Azevedo12, Walber P Vieira13, Elisa N Albuquerque14, Washington A Bianchi15, Rubens Bonfiglioli16, Cristiano Campanholo17, Hellen M S Carvalho18, Angela L B Pinto Duarte19, Charles L Kohem20, Nocy H Leite21, Sonia A L Lima22, Eduardo S Meirelles23, Ivânio A Pereira24, Marcelo M Pinheiro25, Elizandra Polito26, Gustavo G Resende27, Francisco Airton C Rocha28, Mittermayer B Santiago29, Maria de Fátima L C Sauma30, Valéria Valim31, Percival D Sampaio-Barros3. 1. Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brasil. Electronic address: izapec@hotmail.com. 2. Instituto Insper de Educac¸ão e Pesquisa, São Paulo, SP, Brasil. 3. Rheumatology Discipline, Universidade de São Paulo, São Paulo, SP, Brasil. 4. Universidade de Brasília, Brasília, DF, Brasil. 5. Hospital Geral de Goiânia, Goiânia, GO, Brasil. 6. Universidade de Campinas, Campinas, SP, Brasil. 7. Universidade Federal do Amazonas, Manaus, AM, Brasil. 8. Pontifícia Universidade Católica, Porto Alegre, RS, Brasil. 9. Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil. 10. Hospital Evangélico de Curitiba, Curitiba, PR, Brasil. 11. Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 12. Universidade Federal do Paraná, Curitiba, PR, Brasil. 13. Hospital Geral de Fortaleza, Fortaleza, CE, Brasil. 14. Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 15. Santa Casa do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 16. Pontifícia Universidade Católica, Campinas, SP, Brasil. 17. Santa Casa de São Paulo, São Paulo, SP, Brasil. 18. Hospital de Base, Brasília, DF, Brasil. 19. Universidade Federal de Pernambuco, Recife, PE, Brasil. 20. Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil. 21. Faculdade de Medicina Souza Marques, Rio de Janeiro, RJ, Brasil. 22. Hospital do Servidor Público Estadual, São Paulo, SP, Brasil. 23. Institute of Orthopedy and Traumatology, Universidade de São Paulo, São Paulo, SP, Brasil. 24. Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil. 25. Universidade Federal de São Paulo, São Paulo, SP, Brasil. 26. Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brasil. 27. Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil. 28. Universidade Federal do Ceará, Fortaleza, CE, Brasil. 29. Escola de Medicina e Saúde Pública, Salvador, BA, Brasil. 30. Universidade Federal do Pará, Belém, PA, Brasil. 31. Universidade Federal do Espírito Santo, Vitória, ES, Brasil.
Abstract
OBJECTIVE: To analyze the results of the application of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in a large series of Brazilian patients with the diagnosis of SpA and establish its correlations with specific variables into the group. METHODS: A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyoarthropathies Study Group (ESSG), attended at 29 referral centers of Rheumatology in Brazil. Clinical and demographic variables, and disease indices (BASDAI, Basfi, Basri, Mases, ASQol) were applicated. The total values of BASDAI were compared to the presence of the different variables. RESULTS: The mean score of BASDAI was 4.20 ± 2.38. The mean scores of BASDAI were higher in patients with the combined (axial + peripheral + entheseal) (4.54 ± 2.38) clinical presentation, compared to the pure axial (3.78 ± 2.27) or pure peripheral (4.00 ± 2.38) clinical presentations (p<0.001). BASDAI also presented higher scores associated with the female gender (p<0.001) and patients who did not practice exercises (p < 0.001). Regarding the axial component, higher values of BASDAI were significantly associated with inflammatory low back pain (p<0.049), alternating buttock pain (p<0.001), cervical pain (p<0.001) and hip involvement (p<0.001). There was also statistical association between BASDAI scores and the peripheral involvement, related to the lower (p=0.004) and upper limbs (p=0.025). The presence of enthesitis was also associated to higher scores of BASDAI (p=0.040). Positive HLA-B27 and the presence of cutaneous psoriasis, inflammatory bowel disease, uveitis and urethritis were not correlated with the mean scores of BASDAI. Lower scores of BASDAI were associated with the use of biologic agents (p<0.001). CONCLUSION: In this heterogeneous Brazilian series of SpA patients, BASDAI was able to demonstrate "disease activity" in patients with axial as well as peripheral disease.
OBJECTIVE: To analyze the results of the application of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in a large series of Brazilian patients with the diagnosis of SpA and establish its correlations with specific variables into the group. METHODS: A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyoarthropathies Study Group (ESSG), attended at 29 referral centers of Rheumatology in Brazil. Clinical and demographic variables, and disease indices (BASDAI, Basfi, Basri, Mases, ASQol) were applicated. The total values of BASDAI were compared to the presence of the different variables. RESULTS: The mean score of BASDAI was 4.20 ± 2.38. The mean scores of BASDAI were higher in patients with the combined (axial + peripheral + entheseal) (4.54 ± 2.38) clinical presentation, compared to the pure axial (3.78 ± 2.27) or pure peripheral (4.00 ± 2.38) clinical presentations (p<0.001). BASDAI also presented higher scores associated with the female gender (p<0.001) and patients who did not practice exercises (p < 0.001). Regarding the axial component, higher values of BASDAI were significantly associated with inflammatory low back pain (p<0.049), alternating buttock pain (p<0.001), cervical pain (p<0.001) and hip involvement (p<0.001). There was also statistical association between BASDAI scores and the peripheral involvement, related to the lower (p=0.004) and upper limbs (p=0.025). The presence of enthesitis was also associated to higher scores of BASDAI (p=0.040). Positive HLA-B27 and the presence of cutaneous psoriasis, inflammatory bowel disease, uveitis and urethritis were not correlated with the mean scores of BASDAI. Lower scores of BASDAI were associated with the use of biologic agents (p<0.001). CONCLUSION: In this heterogeneous Brazilian series of SpA patients, BASDAI was able to demonstrate "disease activity" in patients with axial as well as peripheral disease.
Authors: Zofia Guła; Tacjana Barczyńska; Marek Brzosko; Jerzy Gąsowski; Sławomir Jeka; Katarzyna Jodłowska-Cicio; Beata Kwaśny-Krochin; Piotr Leszczyński; Łukasz Lubiński; Katarzyna Łosińska; Katarzyna Pawlak-Buś; Hanna Przepiera-Będzak; Włodzimierz Samborski; Małgorzata Schlabs; Maciej Siedlar; Dorota Sikorska; Jerzy Świerkot; Małgorzata Węgierska; Piotr Wiland; Mariusz Korkosz Journal: Reumatologia Date: 2017-04-28
Authors: Anand Kumar; Dana Lukin; Robert Battat; Monica Schwartzman; Lisa A Mandl; Ellen Scherl; Randy S Longman Journal: J Gastroenterol Date: 2020-05-04 Impact factor: 7.527
Authors: D Lai; G Funez-Depagnier; L Duenas-Bianchi; A Lavergne; R Battat; W Ahmed; M Schwartzman; S Lima; S Khan; P S Chong; G Sonnenberg; D Artis; D Lukin; E Scherl; R S Longman Journal: Gastro Hep Adv Date: 2022-02-07