Liang Sun1, Guo-qiang Li1, Peng-bo Yan1, Yang Liu1, Guo-feng Li1, Lu-Qing Wei2. 1. Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China. 2. Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China. Electronic address: sunliangys@sina.com.
Abstract
BACKGROUND: Acute organophosphorus pesticide poisoning during pregnancy may lead to spontaneous abortion. Now, there is no definite strategy focused on maintaining pregnancy. METHOD: This is a retrospective analysis of 2 cases of organophosphorus poisoning during pregnancy. All patients received penehyclidine hydrochloride injection,until the tracheobronchial tree is cleared of the secretions, and most secretions were dried. In addition, magnesium sulfate was used in one woman for the correction of hyperdynamic uterine activity. RESULTS: Two women all survived, one fetus died of spontaneous abortion, and one fetus died of incoordinate uterine action. The 2 women had no significant complications during postpartum period. CONCLUSION: Penehyclidine hydrochloride and magnesium sulfate may be used to treat organophosphorus during pregnancy. However, futher study and new experimental need to be designed.
BACKGROUND: Acute organophosphorus pesticide poisoning during pregnancy may lead to spontaneous abortion. Now, there is no definite strategy focused on maintaining pregnancy. METHOD: This is a retrospective analysis of 2 cases of organophosphorus poisoning during pregnancy. All patients received penehyclidine hydrochloride injection,until the tracheobronchial tree is cleared of the secretions, and most secretions were dried. In addition, magnesium sulfate was used in one woman for the correction of hyperdynamic uterine activity. RESULTS: Two women all survived, one fetus died of spontaneous abortion, and one fetus died of incoordinate uterine action. The 2 women had no significant complications during postpartum period. CONCLUSION:Penehyclidine hydrochloride and magnesium sulfate may be used to treat organophosphorus during pregnancy. However, futher study and new experimental need to be designed.
Authors: Spencer W Todd; Eric W Lumsden; Yasco Aracava; Jacek Mamczarz; Edson X Albuquerque; Edna F R Pereira Journal: Neuropharmacology Date: 2020-08-16 Impact factor: 5.250
Authors: Shi-Yuan Yu; Yan-Xia Gao; Joseph Walline; Xin Lu; Li-Na Zhao; Yuan-Xu Huang; Jiang Tao; An-Yong Yu; Na Ta; Ren-Ju Xiao; Yi Li Journal: World J Emerg Med Date: 2020