Literature DB >> 2554169

Non-NMDA receptor-mediated neuronal injury in Alzheimer's disease?

D W Choi1.   

Abstract

The foregoing review by J. T. Greenamyre and A. B. Young provides an excellent discussion of the alterations in excitatory amino acid transmitter systems that accompany Alzheimer's disease, and the interesting possibility that excitotoxicity may participate in disease pathogenesis. I would add a speculation that non-NMDA receptors may be particularly important in mediating such excitotoxicity.

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Year:  1989        PMID: 2554169     DOI: 10.1016/0197-4580(89)90145-0

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN: 0197-4580            Impact factor:   4.673


  2 in total

Review 1.  Glutamate: its role in learning, memory, and the aging brain.

Authors:  W J McEntee; T H Crook
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

2.  Altered mRNA editing and expression of ionotropic glutamate receptors after kainic acid exposure in cyclooxygenase-2 deficient mice.

Authors:  Luca Caracciolo; Alessandro Barbon; Sara Palumbo; Cristina Mora; Christopher D Toscano; Francesca Bosetti; Sergio Barlati
Journal:  PLoS One       Date:  2011-05-12       Impact factor: 3.240

  2 in total

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