Literature DB >> 25541006

Validity of procalcitonin for the diagnosis of bacterial infection in elderly patients.

Juan Manuel Gómez-Cerquera1, Rafael Daroca-Pérez2, Ramón Baeza-Trinidad2, Marta Casañas-Martinez2, Jose Daniel Mosquera-Lozano2, Enrique Ramalle-Gómara3.   

Abstract

INTRODUCTION: PCT has been consolidated as a key tool in the diagnosis of bacterial infections in general population. Few studies have been conducted to determine the applicability of this test in elderly patients.
METHODS: Study of validity of PCT on elderly patients. Two groups were formed; the first group was formed by patients aged 75 years or older, under bacterial infection criteria and PCT on the initial Lab test. The second group was formed by patients aged 75 years or older with any noninfectious disease; these patients were asked PCT in the initial Lab test. Sensitivity, specificity, positive and negative likelihood ratio were calculated.
RESULTS: 161 patients were included, 95 with probable bacterial infection and 66 without infection. Patients with probable bacterial infection criteria, 72% of them had PCT >0.5 ng/mL. Patients without infection, 8% of the patients had PCT >0.5 ng/mL. Sensitivity and specificity of PCT to bacterial infection with the cutoff value of 0.5 ng/mL was 72% and 92%, respectively.
CONCLUSION: PCT can be used in elderly patients to diagnose bacterial infections because it has proved good sensitivity and high specificity.
Copyright © 2014 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

Entities:  

Keywords:  Bacterial infection; Elderly patients; Infección bacteriana; Pacientes ancianos; Procalcitonin; Procalcitonina

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Year:  2014        PMID: 25541006     DOI: 10.1016/j.eimc.2014.10.019

Source DB:  PubMed          Journal:  Enferm Infecc Microbiol Clin        ISSN: 0213-005X            Impact factor:   1.731


  3 in total

1.  Procalcitonin is not an independent predictor of 30-day mortality, albeit predicts pneumonia severity in patients with pneumonia acquired outside the hospital.

Authors:  Takanori Akagi; Nobuhiko Nagata; Hiroyuki Miyazaki; Taishi Harada; Satoshi Takeda; Yuji Yoshida; Kenji Wada; Masaki Fujita; Kentaro Watanabe
Journal:  BMC Geriatr       Date:  2019-01-07       Impact factor: 3.921

2.  Continuous elevation of procalcitonin in cirrhosis combined with hepatic carcinoma: a case report.

Authors:  Juan Lu; Chun-Lei Chen; Jian-di Jin; Jun Chen; Cheng-Bo Yu
Journal:  BMC Infect Dis       Date:  2021-01-07       Impact factor: 3.090

3.  A Clinical Diagnostic Study: Fibulin-2 is a Novel Promising Biomarker for Predicting Infection.

Authors:  Shidan Li; Hao Jiang; Wei Xing; Shaochuan Wang; Yao Zhang; Youbin Li; Chengyi Mao; Delian Zeng; Ping Lan; Dongqin Tang; Jijie Zhan; Lei Li; Xiang Xu; Jun Fei
Journal:  Infect Dis Ther       Date:  2022-03-18
  3 in total

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